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前庭性偏头痛相关基因的研究进展
Research progress of genes related to vestibular migraine
【摘要】 前庭偏头痛(VM)是一种急性前庭综合征,被认为是复发性眩晕最常见的原因之一,眩晕发作时可能出现自发性或体位性眩晕、视觉引起的眩晕及视物模糊等临床表现,其主要诊断依据是偏头痛发作期间的病史和偏头痛症状。越来越多的研究表明,影响VM的主要因素就是基因变异,目前偏头痛的相关基因尚在研究中,具体有多少种相关性基因尚不明确,本文的目的是研读偏头痛相关基因的文献并予以综述。
【Abstract】 Vestibular migraine(VM) is an acute vestibular syndrome, which is considered to be one of the most common causes of recurrent vertigo. During the onset of vertigo, spontaneous or postural vertigo, visual vertigo,blurred vision and other clinical manifestations may occur. Its main diagnostic basis is the history during the onset of migraine and symptoms of migraine. More and more studies have shown that the main factor affecting VM is gene variation. At present, the genes related to migraine are still under study, and the specific number of related genes is not clear. This paper is intended to study and summarize the literature of migraine related genes.
【Key words】 Vestibular migraine; SCN1A gene; SLC1A3 gene; PBMC gene expression profile; Early growth response gene 1; CAV1 gene; KCNA1 gene; TRPM7 gene; CACNA1A gene; ATP1A2 gene;
- 【文献出处】 中国医药科学 ,China Medicine and Pharmacy , 编辑部邮箱 ,2022年22期
- 【分类号】R747.2
- 【下载频次】6