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卡拉胶水凝胶在生物医学领域中的应用进展
Progress in application of carrageenan hydrogel in biomedicine
【摘要】 卡拉胶(Carrageenan, CG)是从红海藻中提取的一类天然硫酸酯多糖,具有优异的生物相容性、生物降解性、抗氧化、抗病毒和抗肿瘤等特性,是一种可靠的绿色基质。以卡拉胶为基底,通过与其它生物材料的结合以及物理或化学交联等交联方式制备的具有各种结构和性质(机械强度、凝胶性质和细胞亲和力)的水凝胶,可以广泛应用于生物医学领域。综述了几种形式的卡拉胶水凝胶以及其在药物递送、创面愈合、组织工程、生物智能传感方面的应用进展,为卡拉胶在生物医学领域的发展提供理论依据。
【Abstract】 Carrageenan(carrageenan, CG), a kind of natural sulfated polysaccharide extracted from red seaweed, is a reliable green matrix, which has excellent biocompatibility, biodegradability, antioxidant, anti-virus and anti-tumor properties. Based on carrageenan, hydrogels with various structures and properties(mechanical strength, gel properties and cell affinity) can be widely applied in biomedicine field by combining with other biomaterials and physical or chemical crosslinking. In this review, several types of Cara glue gels and their applications in drug delivery, wound healing, tissue engineering, and biosensor are reviewed, providing theoretical basis for the development of carrageenan in biomedicine.
【Key words】 carrageenan; type of hydrogel; wound dressing; drug delivery; tissue engineering; biological intelligent sensor;
- 【文献出处】 功能材料 ,Journal of Functional Materials , 编辑部邮箱 ,2022年03期
- 【分类号】R318.08
- 【下载频次】985