【摘要】 目的 研究石蜡油用作24 h尿蛋白定量标本保存防腐剂的应用效果。方法 筛选尿干化学检测尿蛋白半定量不同梯度的标本共20例，即时用生化分析仪检测尿蛋白定量结果并作为对照组，分样标本按照保存温度、防腐剂类型、保存时间等因素组合设计12个配对试验组，运用SPSS 25统计软件对试验组测定值与对照组检测值进行比较。结果 各试验组与对照组经多个相关样本Fredman检验，结果提示各组间差异无统计学意义(P>0.05)。多因素方差分析结果提示各防腐剂类型、保存温度、保存时间各因素及其交互效应，对24 h尿蛋白定量无影响(P>0.05)。结论 保存温度、防腐剂的类型、保存时间对24 h尿蛋白定量标本保存无影响，综合考虑石蜡油用作24 h尿蛋白定量标本防腐剂常温保存具有安全无毒、操作方便等优点，值得向业内广泛推广。更多还原

【Abstract】 Objective To analysis the effect of liquid oil as a nontoxic specimen preservative for 24-hour urine protein.Methods Twenty specimens with different urine protein results of urine dipsticks analysis were collected. The urine protein was measured on automatic biochemistry analyzer and the result was used as reference value. Each specimen was split to 12 tubes according to combination of temperature, preservative and storage time. Data were processed with SPSS statistic 25 software. Results Data of control group and 12 study groups did not show significant difference by Fredman′s rank test(P>0.05). Results by multi-factor variance analysis implied that temperature, preservative and storage time plus interactions of them had no effect on 24-hour urine protein specimen storage(P>0.05). Conclusion Comprehensively liquid oil was a nontoxic and convenient preservative for 24-hour urine protein specimen, and it is worth of extensive application in clinical laboratory.更多还原