【摘要】 目的:研究正常人群乳腺癌筛查钼靶结果显示不清，即乳腺影像报告和数据系统(BIRADS)分类为0的受检者的检出率、就诊及一年转归情况，分析讨论钼靶BIRADS-0类的临床现状。方法:回顾性分析2018年1月-2019年12月至复旦大学附属妇产科医院体检中心进行乳腺癌筛查并进行钼靶检查者的临床资料，统计钼靶BIRADS-0类的检出率，并统计其就诊和转归情况，分析临床中BIRADS-0类患者的就诊情况及转归。筛选其中261例接受钼靶检查并结果异常需要就诊的女性体检者的临床资料，根据钼靶结果中BIRADS分类分为A组(BIRADS-4类，可疑恶性)和B组(BIRADS-0类，显示不清)。采用t检验比较两组年龄情况，卡方检验比较各组的检出情况及转归，Kappa检验评估对两组完善超声意愿的一致性。结果:2018年1月-2019年12月我中心乳腺癌检出率48.9/10万，入组的受检者平均年龄为(47.02±6.82)岁；A组(BIRADS-4类)61.65%进一步完善了超声检查，B组(BIRADS-0类)有46.87%进一步完善了超声检查；在1年的随访中，共确诊9例乳腺癌，同时发现9例病情进展，在40岁以上的患者中，A组(BIRADS-4类)有4例出现病情进展，B组(BIRADS-0类)有5例出现病情进展，两组差异有统计学意义(P=0.022)。结论:钼靶BIRADS-0病例可能隐匿恶性病灶，有必要及时联合其他检查明确病情，目前体检者对钼靶BIRADS-0的结果认知和重视程度相对较低，需提高认知。更多还原

【Abstract】 Objective:To study the detection rate, consultation, and one-year outcome of mammography breast imaging reporting and data system(BIRADS)-0,and to discuss the present clinical status of mammography BIRADS-0.Methods:We retrospectively analyze the clinical data of patients who underwent breast cancer screening with mammography at the Medical Examination Center of Obstetrics and Gynecology Hospital of Fudan University from Jan 2018 to Dec 2019,the detection rate, consultation, and one-year outcome of mammography BIRADS-0 were collected and analyzed.The clinical data of 261 women who underwent mammography and had abnormal results requiring consultation were observed and divided into Group A(BIRADS-4,suspicious malignancy) and Group B(BIRADS-0,indistinct display) according to the BIRADS classification in mammography results.The T-test was used to compare the age of two groups, the Chi-square test was used to compare the detection and regression of each group, and the Kappa test was used to evaluate the agreement of the willingness to perfect the ultrasound in both groups.Results:The detection rate of breast cancer in our center was 48.9/10 million from January 2018 to December 2019.The mean age of the enrolled subjects was 47.02±6.82 years old.61.65% of patients in Group A and 46.87% in Group B further underwent ultrasound examinations.A total of nine breast cancer cases were confirmed and nine patients were found to be progressive after 1-year follow-up.In patients over 40 years old, four cases in Group A(BIRADS-4) and five cases in Group B(BIRADS-0) showed progression, with a statistically significant difference between the two groups(P=0.022).Conclusion:Mammography BIRADS-0 cases may conceal malignant lesions, and it is necessary to clarify the disease timely in combination with other examinations.The awareness and importance of mammography BIRADS-0 results among can breast cancer screening people is relatively low and need to be improved.更多还原