【摘要】 目的 探讨前路与后路减压融合术治疗颈椎后纵韧带骨化症（OPLL）的临床效果。方法 选取该院2019年8月—2021年4月收治的150例OPLL患者为研究对象，按照随机数字表法分为对照组和观察组，每组75例。对照组采用后路减压融合术，观察组采用前路减压融合术，随访至术后3个月。比较两组的围术期指标、疼痛程度、椎体功能及并发症发生情况。结果 观察组的手术时长长于对照组，术中出血量少于对照组，组间差异有统计学意义（P<0.05）。术后15、30 d，观察组的视觉模拟评分低于对照组，术后3个月，观察组的颈椎骨科协会评估治疗评分（JOA）评分高于对照组，组间差异有统计学意义（P<0.05）。住院期间，观察组并发症总发生率与对照组相比，差异无统计学意义（P>0.05）。结论 前路与后路减压融合术治疗OPLL均有显著疗效，前路减压融合术可减少患者术中出血量，减轻机体疼痛程度，提高颈椎功能，后路减压融合术可缩短手术时间，临床中可根据患者实际情况选择适宜的术式。更多还原

【Abstract】 Objective To investigate the clinical effect of anterior and posterior decompression and fusion in the treatment of ossification of cervical posterior longitudinal ligament(OPLL). Methods A total of 150 OPLL patients admitted to our hospital from August 2019 to April 2021 were selected as the research objects, and divided into the control group and the observation group according to the random number table method, with 75 cases in each group. The control group was treated with posterior decompression and fusion, while the observation group was treated with anterior decompression and fusion. The patients were followed up for 3 months after operation. The perioperative indicators, pain degree, vertebral body function and complications were compared between the two groups. Results The operation time of the observation group was longer than that of the control group, and the intraoperative blood loss was less than that of the control group, and the differences between the groups were statistically significant(P<0.05). At 15 and 30 days after operation, the visual analogue scale score of the observation group was lower than that of the control group, at 3 months after operation, the Japanese Orthopaedic Association(JOA) cervical spine score of the observation group was higher than that of the control group, and the differences between the groups were statistically significant(P <0.05). During hospitalization, there was no significant difference in the total incidence of complications between the observation group and the control group(P>0.05). Conclusion Both anterior and posterior decompression and fusion have significant curative effects in the treatment of OPLL. Anterior decompression and fusion can reduce the amount of intraoperative blood loss, reduce body pain, and improve cervical spine function. Posterior decompression and fusion can shorten the operation time, and the appropriate surgical method can be selected according to the actual situation of the patient.更多还原