【摘要】 目的:明确临床药师科普干预的重要性，探索儿科临床药师进行科普干预的有效方法，从而提高患者用药依从性，提升临床疗效，减少再住院率。方法:选取厦门市中医院2020年3-8月诊断为社区获得性肺炎住院患者，随机分为对照组和科普干预组各50例，其中科普干预组又进一步分为西药临床药师科普干预组25例和中西药临床药师联合科普干预组25例，分别进行临床疗效、用药依从性、科普知识知晓率、再住院率评价。结果:在提高临床疗效方面，科普干预组体温恢复正常时间、咳嗽及肺部体征明显好转时间、出院时间较对照组短，差异均有统计学意义(P<0.05),西药科普干预组和中西药联合科普干预组比较差异无统计学意义(P>0.05)。在提高患者用药依从性方面，中西药联合科普1次即有明显效果，单纯西药科普2次有明显效果。随访6个月内对照组有2例患儿因肺炎再次入院，科普组无患儿因肺炎再次入院。结论:患儿的安全用药教育刻不容缓，临床药师的科普宣教在提升患者用药依从性、提高临床疗效方面成效显著。更多还原

【Abstract】 Objective: To clarify the importance of science promotion intervention by clinical pharmacists, explore the effective methods of science promotion intervention by pediatric clinical pharmacists, so as to improve patients’ medication compliance, promote the clinical efficacy and reduce the readmission rate. Methods: Inpatients diagnosed with community-acquired pneumonia in Xiamen Hospital of Traditional Chinese Medicine from Mar. to Aug. 2020 were randomly divided into the control group and the science promotion intervention group, with 50 cases in each group. The science promotion intervention group was further divided into the science promotion intervention by clinical pharmacists of western medicine group and the science promotion intervention by clinical pharmacists of tradition Chinese and Western medicine group, with 25 cases in each group. The clinical efficacy, medication compliance, science knowledge awareness rate and readmission rate were evaluated respectively. Results: In terms of improving the clinical efficacy, compared with the control group, the recovery time of body temperature, the disappearance time of cough and lung signs, and length of stay in the science promotion intervention group were shorter, with statistically significant differences(P<0.05), and there was no statistical significance between the science promotion intervention by clinical pharmacists of western medicine group and the science promotion intervention by clinical pharmacists of tradition Chinese and western medicine group(P>0.05). In terms of improving medication compliance, the science promotion intervention of combination of traditional Chinese and western medicine for once had significant effects, and the simple science promotion of western medicine for twice had significant effects. Within 6 months of follow-up, two children in the control group were readmitted due to pneumonia, and none of the children in the science promotion intervention group was readmitted due to pneumonia. Conclusion: The education of safe drug use for children is urgent, and the science promotion intervention by clinical pharmacists has significant effects on improving the medication compliance and clinical efficacy of patients.更多还原