【摘要】 目的 通过对婴儿痉挛症患儿的远期随访以了解该疾病的预后情况。方法 回顾性分析2010年1月—2015年12月在重庆医科大学附属儿童医院诊断并治疗的婴儿痉挛症患儿。收集其临床资料，并对其进行生存情况电话随访。结果 共收集到病例资料169份，成功有效随访到59例，其中可上学组13例、不可上学组38例、死亡8例。未上学组38例，其中不可行走17例，占未上学组44.74%；不能跑27例，占未上学组71.05%；不能自行进食，需家人照顾33例，占未上学组86.84%。不能说简单句子的患儿36例，占94.74%。此外，在癫痫发作方面，5年以上无发作共15例，占存活组人数29.41%。结论 婴儿痉挛症的远期预后差占比大，死亡率为13.56%，存活组中上学率为25.5%，未上学组自理生活能力均较差。而起病时的发育正常和癫痫早期控制无发作是该病预后的重要影响因素。更多还原

【Abstract】 Objective To understand the prognosis of infantile spasm through long-term follow-up. Methods Children with infantile spasm diagnosed and treated in Children’s Hospital from January 2010 to December 2015 were retrospectively analyzed. Clinical data were collected and telephone follow-up was conducted. Results A total of 174 cases were collected, 59 cases were successfully followed up, of which 13 were in the school attendance group. 38 students were not allowed to go to school, Eight people were dead. In the group that did not go to school, 17 of them could not walk, accounting for 44.74% of the group that did not go to school, 27 of them could not run, accounting for about 71.05%of the group that did not go to school. The number of people who could not feed themselves and needed family care was33, accounting for 86.84% of the non-school group.There were 36 children who could not speak simple sentences,accounting for about 94.74%. In addition, in terms of seizures, there were 15 patients without seizures for more than 5years, accounting for 29.41% of the survival group. Conclusion The proportion of people with poor long-term prognosis of infantile spasm is large, and they are often unable to take care of themselves and need family care. The main reasons for being unable to go to school and participate in social activities are language, intelligence, and self-care.更多还原