【摘要】 目的 探究早期显微手术夹闭瘤颈治疗脑动脉瘤破裂出血的临床疗效及对患者预后的影响。方法 选取2019年6月至2020年6月本院收治的50例脑动脉瘤破裂出血患者作为研究对象，均行显微手术夹闭瘤颈治疗，按照手术时间分为观察组与对照组，每组25例。比较两组并发症发生率、预后优良率、手术指标及术后蒙特利尔认知评估量表（MoCA）各项评分。结果 观察组并发症发生率低于照组，差异有统计学意义（P<0.05）。观察组预后优良率高于对照组，差异有统计学意义（P<0.05）。两组手术时间、住院时间、术中出血量比较差异无统计学意义。观察组命名、抽象、语言、定向、注意力、延迟回忆、视觉与执行能力评分及总分均高于对照组，差异有统计学意义（P<0.05）。结论 脑动脉瘤破裂出血患者予以早期显微手术夹闭瘤颈疗效显著，可强化患者远期疗效，降低并发症发生风险，减少认知功能损伤，值得临床推广应用。更多还原

【Abstract】 Objective To explore the clinical efficacy of early microsurgical clipping of the tumor neck in the treatment of cerebral aneurysm rupture and bleeding and its influence on the prognosis of patients. Methods 50 patients with cerebral aneurysm rupture and bleeding admitted from June 2019 to June 2020 were selected as the study subjects, and all underwent microsurgical occlusion neck treatment, and they were divided into observation group and control group according to the operation time, with 25 cases in each group. The incidence of complications, excellent prognosis,surgical indicators and postoperative Montreal cognitive assessment(MoCA) scores were compared between the two groups. Results The incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05). The good prognosis rate in the observation group was higher than that in the control group, the difference was statistically significant(P<0.05). There was no significant difference between the operation time, hospitalization time and intraoperative bleeding between the two groups. The naming, abstraction, language, orientation, attention, delayed recall, visual and executive ability score and total score in the observation group were all higher than those in the control group, the difference was statistically significant(P<0.05). Conclusion Early microsurgery clipping of the tumor neck in patients with cerebral aneurysm rupture and bleeding has significant curative effect, which can enhance the long-term efficacy of patients, reduce the risk of complications, and reduce cognitive impairment, it is worthy of clinical application.更多还原