【摘要】 目的 分析脊柱良性与侵袭骨母细胞瘤临床表现及CT、MRI征象。方法 回顾分析，收集本院2015年9月至2019年10月收治的良性骨母细胞瘤(BO)、侵袭性骨母细胞瘤(AO)患者临床资料为研究对象各18例。所有患者均进行CT及MRI检查。对患者所得CT及MRI图像进行分析，并了解AO、BO患者临床表现。结果 BO患者年龄比AO组小，病程比AO患者长，累及临近骨、神经损伤方面低于AO组(P<0.05)；两者在病灶无钙化或骨化灶、骨皮质不完整、病变周围有斑块状骨质硬化情况上有明显差异(P<0.05),BO患者骨质均出现膨胀性改变，患者病灶内钙化或骨化灶情况，且患者骨皮质均完整、病变周围有均有斑块状骨质硬化。AO患者中有88.88%骨质出现膨胀性改变，72.22%病灶内钙化或骨化灶，骨质均不完整，66.66%缓存病变周围有斑块状骨质硬化存在；两者在病灶周围水肿情况上有明显差异(P<0.05)，两组患者MRI信号上并无明显特异性，两者病灶周围均有水肿现象，但BO患者多于AO患者；两者均存在不同程度硬膜囊及脊髓受压情况。结论 BO患者与AO患者在临床表现、影像学表现上存在差异，通过分析影像学及临床表现可对两者进行相关鉴别。更多还原

【Abstract】 Objective To analyze the clinical manifestations and CT and MRI signs of benign and aggressive osteoblastoma of the spine. Methods The clinical data of patients with benign osteoblastoma(BO) and invasive osteoblastoma(AO) treated in our hospital from september 2015 to October 2019 were collected and retrospectively analyzed, 18 patients in each group. The CT and MRI images of the patients were analyzed, and the clinical manifestations of AO and BO patients were understood. Results Patients with BO are younger than patients with AO, have a longer course of disease,and have lower damage to adjacent bones than those in the AO group(P<0.05). There was significant difference between them in the absence of calcification or ossification, incomplete bone cortex, and plaque-like sclerosis around the lesion(P<0.05). The sclerotin of patients with BO all showed expansive changes. There were calcification or ossification in the lesions, and the patients had intact bone cortex and plaque-like sclerosis around the lesions. In AO patients, 88.88% of the sclerotin exhibited expansive changes, 72.22% of the lesions had calcification or ossification, and the sclerotin were incomplete. Plaque-like osteosclerosis exists around 66.66% buffer lesions. There was a significant difference between themin the edema around the lesion(P<0.05). There was no significant specificity in the MRI signals between the two groups. There was edema around the lesions in both groups, but BO patients were more than AO patients. Both they have different degrees of compression of the dural sac and spinal cord. Conclusion There are differences in clinical manifestations and imaging findings between BO and AO patients. By analyzing the imaging and clinical manifestations, them can be identified.更多还原