【摘要】 目的探究颅内动脉瘤介入与夹闭手术中应用CT灌注成像评估效果差异。方法回顾性分析2011年1月至2019年1月我院收治的颅内动脉瘤患者相关资料，依据患者治疗方式不同将采用血管介入栓塞与开颅瘤颈夹闭方式治疗患者分别纳入栓塞组(n=234)与夹闭组(n=56)，两组患者均接受CT灌注成像检查。结果两组患者手.术后MTT、CBF以及CVB等灌注参数显著变化(P<005)，手术.后栓塞组患者CBF与CVB明显低于夹闭组患者(P<0.05)，两组之间MTT比较差异没有统计学意义(P>005)。栓塞组患者随访期间.血管痉挛、脑梗死发生率显著低于夹闭组患者(P<005)，两组.患者随访期间死亡发生率差异没有统计学意义(P>005)。血管.痉挛患者CBF与CVB显著低于非血管痉挛患者(P<.005)，脑梗死患者CBF明显低于非脑梗死患者(P<005)；血管痉挛与非血管痉挛患者患者MTT，脑梗死与非脑梗死患者MTT与CVB，死亡与非.死亡患者MTT、CBF与CVB差异没有统计学意义(P>005)。结论CT灌注成像相关灌注指标在评估颅内动脉瘤介入栓塞和闭夹手术后颅脑血流、预后情况尤其是血管痉挛与脑梗死上效果显著。更多还原

【Abstract】 Objective To explore differences in evaluation effect of CT perfusion imaging for intracranial aneurysm intervention and clapping surgery. Methods A retrospective analysis was performed on related data of patients with intracranial aneurysms who were admitted to the hospital from January 2011 to January 2019. According to different treatment methods, patients who were treated with vascular interventional embolization or craniotomy aneurism clapping were included in embolization group(n=234) and clapping group(n=56). Both groups underwent CT perfusion imaging examination. Results After surgery, perfusion parameters such as MTT, CBF and CVB in both groups were significantly changed(P<0.05). After surgery, CBF and CVB in embolization group were significantly lower than those in clapping group(P<0.05). There was no significant difference in MTT between the two groups(P>0.05). During follow-up, incidence of vasospasm and cerebral infarction in embolization group was significantly lower than that in clapping group(P<0.05). There was no significant difference in mortality between the two groups(P>0.05). CBF and CVB in patients with vasospasm were significantly lower than those without vasospasm(P<0.05). CBF in patients with cerebral infarction was significantly lower than without cerebral infarction(P<0.05). There was no significant difference in MTT between vasospasm patients and non-vasospasm patients, MTT and CVB between cerebral infarction patients and non-cerebral infarction patients, MTT, CBF and CVB between death patients and non-death patients(P>0.05). Conclusion The effects of CT perfusion imaging related perfusion indexes are significant on evaluating blood flow and prognosis(especially for vasospasm and cerebral infarction) after intracranial aneurysms interventional embolization and clapping surgery.更多还原