【摘要】 目的：研究结节性甲状腺肿患者的碘营养状况，并分析尿碘水平与结节性甲状腺肿的相关性。方法：选取2018年1月～2020年5月于我院确诊为结节性甲状腺肿的353例患者作为病例组，同期于本院体检排除甲状腺疾病的健康人群179例作为对照组。比较两组人群的尿碘含量，分析病例组尿碘水平与促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、甲状腺球蛋白抗体(TgAb)的相关性。结果：病例组尿碘水平为163.91±112.82μg/L,高于健康人群组122.47±58.60μg/L(P<0.05)。病例组中女性碘过量率高于男性(P<0.05)。相关分析显示，病例组尿碘水平与FT3、FT4、TSH、TgAb无明显相关性(均P>0.05)。结论：本地区结节性甲状腺肿人群碘营养状况基本处于碘适量水平；但尿碘水平与结节性甲状腺肿患者的甲状腺功能指标无关。更多还原

【Abstract】 Objective: To investigate the iodine nutritional status of patients with nodular goiter, and analyze the correlation between urinary iodine and nodular goiter. Methods: A total of 353 cases of nodular goiter diagnosed in our hospital were selected as the case group, and 179 healthy persons without any thyroid diseases were selected as the control group. Then urine iodine level were compared between two groups. The correlation between urine iodine level and free triiodothyronine(FT3), free thyroxine(FT4), thyroid-stimulating hormone(TSH) or thyroglobulin antibody(TgAb) in the case group were analyzed. Results: The urinary iodine level of the case group was 163.91±112.82 μg/L, which was higher than that of the control group(122.47±58.60 μg/L)(P<0.05). The iodine excess rate of female was higher than that of male in the case group(P<0.05). There was no significant correlation between urine iodine and FT3, FT4, TSH or TgAb in the case group(all P>0.05).Conclusion: The iodine nutritional status of nodular goiter population in this area is basically at the appropriate level. Urinary iodine level may have no significant correlation to thyroid function in patients with nodular goiter.更多还原