【摘要】 目的 探讨前入路肝右半切除术在肝癌中的应用价值。方法 根据治疗方式的不同将65例肝癌患者分为对照组（n=32）和观察组（n=33），对照组患者给予常规入路肝切除术治疗，观察组患者给予前入路肝切除术治疗。比较两组患者的手术相关指标、炎症因子[白细胞介素（IL）-6、IL-8、肿瘤坏死因子-α(TNF-α)，计算中性粒细胞与淋巴细胞比值（NLR）]、肝功能指标[谷丙转氨酶（ALT）、谷草转氨酶（AST）]和术后并发症发生情况。结果 观察组患者平均出血量少于对照组（P﹤0.05），输血率和肿瘤破裂率均低于对照组（P﹤0.05），住院时间短于对照组（P﹤0.05）。术后7天，两组患者IL-6、TNF-α、IL-8水平和NLR均高于本组术前（P﹤0.05），但观察组患者IL-6、TNF-α、IL-8水平和NLR均低于对照组（P﹤0.05）。术后7天，两组患者AST、ALT水平均高于本组术前（P﹤0.05），但观察组患者AST、ALT水平均低于对照组（P﹤0.05）。两组患者腹腔感染、腹腔出血、胆瘘、肺部感染并发症发生率均无明显差异（P﹥0.05）。结论 前入路右半肝切除术可有效减轻肝癌患者的炎症反应，改善肝功能指标，促进术后恢复。更多还原

【Abstract】 Objective To investigate the application value of anterior right hepatectomy in the treatment of liver cancer. Method According to different treatment methods, 65 patients with liver cancer were divided into control group(n=32) and observation group(n=33). The patients in the control group were treated with conventional approach hepatectomy, and the patients in the observation group were treated with anterior approach hepatectomy. The operation-related indexes, inflammatory factor [interleukin-6(IL-6), interleukin-8(IL-8)、tumor necrosis factor-α(TNF-α), and calculate neutrophil-to-lymphocyte ratio(NLR)], liver function indexes [alanine aminotransferase(ALT), aspartate aminotransferase(AST)] and postoperative complications were compared between the two groups. Result The average blood loss in the observation group was less than that in the control group(P<0.05), the blood transfusion rate and tumor rupture rate were lower than those in the control group(P<0.05), and the length of hospital stay was shorter than that in the control group(P<0.05). 7 days after operation, the IL-6, TNF-α, IL-8 and NLR were higher than those before operation(P<0.05), but the levels of IL-6, TNF-α, IL-8 and NLR in the observation group were lower than those in the control group(P<0.05). 7days after operation, the levels of AST and ALT in the two groups were higher than those before operation(P<0.05), but the levels of AST and ALT in the observation group were lower than those in the control group(P<0.05). There was no significant difference in the incidence of complications such as intra-abdominal infection, intra-abdominal hemorrhage,biliary fistula, and pulmonary infection between the two groups(P>0.05). Conclusion Anterior right hepatectomy can effectively reduce the inflammatory response in patients with liver cancer, improve liver function indicators, and promote postoperative recovery.更多还原