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铁死亡在头颈部肿瘤中的研究进展

Research progress in ferroptosis in head and neck cancer

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【作者】 黄议莹温文胜

【Author】 HUANG Yiying;WEN Wensheng;Department of Otolaryngology-Head and Neck Surgery,The First Affiliated Hospital of Guangxi Medical University;Guangxi Key Laborator y of Early Prevention and Treatment for Regional High Frequency Tumor;

【通讯作者】 温文胜;

【机构】 广西医科大学第一附属医院耳鼻咽喉头颈外科广西区域性高发肿瘤早期防治研究重点实验室

【摘要】 铁死亡是新发现的一种调节性细胞死亡形式。近期研究发现,铁死亡在肿瘤治疗中显示出巨大的应用潜力,已在呼吸系统、泌尿系统和神经系统肿瘤中得到了验证。头颈部肿瘤是常见的恶性肿瘤,而铁死亡在头颈部肿瘤中的研究和应用还较少。本文对铁死亡在头颈部肿瘤中的研究进展进行综述,以期为头颈部肿瘤的治疗增敏提供新的策略和方向。

【Abstract】 Ferroptosis h is a newly discovered form of regulatory cell death. Recent studies have found that ferroptosis shows great application potential in cancer therapy, which has been verified in cancer of respiratory, urinary and nervous systems. Head and neck cancer is common malignant tumors,but the research and application of ferroptosis in head and neck cancer are still less. This paper reviews the research progress in ferroptosis in head and neck cancer, in order to provide a new strategy and direction for the treatment and sensitization of head and neck cancer.

【基金】 国家自然科学基金(81860479);广西自然科学基金(2018GXNSFBA281028)~~
  • 【分类号】R739.91
  • 【下载频次】49
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