【摘要】 目的探讨氦氖激光照射治疗细菌性肝脓肿(pyogenic liver abscess, PLA)的价值。方法回顾性分析2016年1月～2019年1月48例PLA的临床资料,依据治疗方案分为2组,每组24例,对照组超声引导下穿刺引流术联合抗炎治疗,研究组在对照组的基础上联合氦氖激光照射治疗,比较2组患者的临床疗效。结果研究组住院时间,体温、白细胞、C-反应蛋白、降钙素原恢复正常时间均较对照组明显缩短[(13.8±2.7)d vs.(17.5±2.8)d,t=4.645,P=0.000;(4.9±1.8)d vs.(6.7±1.8)d,t=3.354,P=0.002;(6.8±1.5)d vs.(7.9±1.6)d,t=2.482,P=0.017;(7.2±1.7)d vs.(8.9±2.1)d,t=3.136,P=0.003;(6.8±2.2)d vs.(8.3±1.8)d,t=2.608,P=0.012]。研究组与对照组脓腔消除时间差异无显著性[(26.4±5.8)d vs.(27.0±5.5)d,t=0.408,P=0.685]。结论氦氖激光照射治疗可以明显缩短PLA患者住院时间和体温、白细胞、C-反应蛋白、降钙素原恢复正常时间,但在缩短脓腔消除时间方面无明显优势。更多还原

【Abstract】 Objective To investigate the application value of He-Ne laser irradiation in the treatment of pyogenic liver abscess(PLA). Methods Clinical data of 48 patients with PLA admitted into our hospital from January 2016 to January 2019 were retrospectively analyzed. According to the treatment methods, the patients were divided into two groups. Patients in the control group were given ultrasound-guided puncture drainage combined with anti-inflammatory treatment, while patients in the study group were treated with He-Ne laser irradiation on the basis of treatment of the control group. Results The hospitalization time and the recovery time of body temperature, white blood cell, C-reactive protein and procalcitonin in the study group were shorter than those in the control group [(13.8±2.7) d vs.(17.5±2.8) d, t=4.645, P=0.000;(4.9±1.8) d vs.(6.7±1.8) d, t=3.354, P=0.002;(6.8±1.5) d vs.(7.9±1.6) d, t=2.482,P=0.017;(7.2±1.7) d vs.(8.9±2.1) d, t=3.136, P=0.003;(6.8±2.2) d vs.(8.3±1.8) d, t=2.608, P=0.012]. There was no significant difference in the elimination time of pus cavity between the study group and the control group [(26.4±5.8) d vs.(27.0±5.5) d, t=0.408, P=0.685]. Conclusion He-Ne laser irradiation can significantly shorten the hospital stay and recovery time of body temperature, white blood cells, C-reactive protein, and procalcitonin in patients with PLA, but it has no obvious advantage in shortening the elimination time of pus cavity.更多还原