【摘要】 目的分析胺碘酮在心力衰竭(心衰)合并快速心房颤动急诊治疗中的应用效果及安全性。方法 30例心衰合并快速心房颤动患者,依据系统抽样法分为对照组及观察组,各15例。对照组接受去乙酰毛花苷注射液(商品名:西地兰)治疗,观察组接受胺碘酮治疗。比较两组治疗效果、心功能指标[左室舒张末期内径(LVEDD)和左室射血分数(LVEF)]、心室率及不良反应发生率。结果观察组治疗总有效率93.33%高于对照组的60.00%,差异有统计学意义(P<0.05)。治疗后,观察组LVEDD和LVEF优于对照组,差异有统计学意义(P<0.05)。治疗后,观察组心室率(78.84±5.65)次/min低于对照组的(84.30±4.59)次/min,差异有统计学意义(P<0.05)。观察组不良反应发生率6.67%低于对照组的46.67%,差异有统计学意义(P<0.05)。结论心衰合并快速心房颤动患者急诊救治过程中,胺碘酮的应用不仅可以改善患者心功能,控制心室率,而且有助于治疗效果提高,安全性高,值得采纳与推广。更多还原

【Abstract】 Objective To analyze the practical effect and safety of amiodarone in emergency treatment of patients with heart failure and rapid atrial fibrillation. Methods A total of 30 patients with heart failure and rapid atrial fibrillation were divided into control group and observation group according to system sampling method, with 15 cases in each group. The control group was treated with deslanoside injection(trade name: Cedilanid), and the observation group was treated with amiodarone. The therapeutic effect, cardiac function indicators [left ventricular end-diastolic diameter(LVEDD) and left ventricular ejection fraction(LVEF)], ventricular rate, and incidence of adverse reactions were compared between the two groups. Results The total effective rate 93.33% of the observation group was higher than 60.00% of the control group, and the difference was statistically significant(P<0.05). After treatment, the LVEDD and LVEF of the observation group were better than those of the control group, and the difference was statistically significant(P<0.05). After treatment, the ventricular rate(78.84± 5.65) beats/min of the observation group was lower than(84.30±4.59) beats/min of the control group, and the difference was statistically significant(P<0.05). The incidence of adverse reactions 6.67% of the observation group was lower than 46.67% of the control group, and the difference was statistically significant(P<0.05). Conclusion In emergency treatment of patients with heart failure and rapid atrial fibrillation, the application of amiodarone can not only improve the cardiac function and control the ventricular rate, but also help to improve the therapeutic effect and safety, which is worth adopting and popularizing.更多还原