【摘要】 目的测定普乐沙福的波谱学特征,确证其化学结构。方法利用红外光谱(IR)、紫外光谱(UV)、核磁共振(NMR)、高分辨质谱(MS)、热分析和X-射线粉末衍射(XRD)等技术对普乐沙福进行结构分析。结果通过解析证实普乐沙福的结构为1,1’-[1,4-亚苯基(亚甲基)]-二-1,4,8,11-四氮杂环十四烷。结论该方法准确可行,可为普乐沙福的质量控制和结构鉴定提供依据。更多还原

【Abstract】 Objective To determine the spectroscopic characteristics and to identify the chemical structure of plerixafor with a variety of analytic techniques.Methods The infrared spectrometry,ultraviolet-visible spectrometry,nuclear magnetic resonance,mass spectrometry,thermal analysis and X-ray powder diffraction were adopted to analyze the chemical structure of plerixafor.Results The chemical structure of plerixafor was determined to be 1,1’-[1,4-phenylenebis (methylene)]bis-1,4,8,11-tetraazacyclotetradecane.Conclusion The method is accurate and reliable,and it can provide a reference for the production control and identification of plerixafor.更多还原