【摘要】 患者,男,32岁,反复淋巴结肿大、发热伴皮疹2年,广谱抗生素、抗结核治疗无效,肺部CT提示两肺内多发结节,血γ干扰素抗体阳性,皮肤活检组织、淋巴结组织、肺穿刺活检组织均培养出马尔尼菲篮状菌,予两性霉素B脂质体联合伏立康唑治疗效果佳。更多还原

【Abstract】 A 32-year-old man was admitted because of recurrent episodes of lymphadenectasis, fever and skin rashes for two years. Broad-spectrum antibiotics and anti-tuberculosis therapy were ineffective. Lung CT showed multiple nodules in both lungs and the serum was positive for anti-IFN-γ. Disseminated Talaromyces marneffei was diagnosed by skin biopsy, lymph node biopsy, lung biopsy. Amphotericin B liposome combined with voriconazole had a good therapeutic effect.更多还原