【摘要】 本文研究采用液相色谱-串联质谱法测定蔬菜产品中吡虫啉的药物残留量,并进行不确定度评定,建立不确定度数学评估模型。通过对测量过程中的不确定来源进行分析评定,计算出不确定度分量,相对合成不确定度,得出不确定度报告。结果表明:影响测定结果不确定度的主要因素为测量重复性引入的不确定度,其次为标准曲线和标准物质定容引入的不确定度。在实际检测过程中,提高液质联用仪的稳定性和灵敏度,增加标准曲线溶液的测定次数,控制标准溶液的配制过程,以及提高检测人员的工作质量都可使检测结果更加可靠。更多还原

【Abstract】 In this paper, the method of ultra high performance liquid chromatography-tandem mass spectrometry is used for the evaluation of the drug residue limits and uncertainty of imidacloprid in vegetables, and a mathematical evaluation model of uncertainty is established. By analyzing the sources of uncertainty in the detection process, the uncertainty components are calculated, and the uncertainty report is obtained by calculating the uncertainty components and combining the relative uncertainties. The results show that the main factors affecting the uncertainty of the determination results are caused by the repeatability of measurement, followed by the standard curve and the constant volume of standard substance. So in the detection process, improving the stability and sensitivity of the LC-MS/MS instrument,increasing the determination times of the standard curve solution, controlling the stability preparation of the standard solution and improving the operation quality of the testing staff can make the determination results more reliable.更多还原