【摘要】 目的分析黑龙江省肿瘤登记地区肝癌发病死亡情况及时间变化趋势。方法收集2013—2017年黑龙江省肿瘤登记地区上报的肝癌发病与死亡资料,计算发病(死亡)率、标化发病(死亡)率、累积率(0～74岁)等,标化率采用2000年全国人口普查标准人口构成和Segi′s世界标准人口构成作为标准。年度变化百分比(APC)使用Joinpoint软件计算。结果 2013—2017年黑龙江省肿瘤登记地区肝癌发病率为29.13/10万,中标率为17.18/10万,累积率(0～74岁)为1.96%。其中男性肝癌发病率(42.59/10万)高于女性(15.90/10万),农村地区肝癌发病率(35.05/10万)高于城市地区(26.75/10万)。2013—2017年黑龙江省肿瘤登记地区肝癌死亡率为26.53/10万,中标率为15.90/10万,累积率(0～74岁)为1.78%。其中男性肝癌死亡率(38.33/10万)高于女性(14.93/10万),农村地区肝癌死亡率(30.65/10万)高于城市地区(24.88/10万)。2013—2017年发病中标率呈下降趋势,死亡中标率无明显变化趋势(P>0.05),男性发病中标率呈下降趋势(P<0.05)。结论黑龙江省肝癌负担较重,发病率整体呈下降趋势,死亡趋势较平稳。防治工作中应重点关注男性及农村地区,采取综合措施进行有效预防与控制。更多还原

【Abstract】 ObjectiveTo analyze the incidence and mortality of liver cancer in cancer registration areas of Heilongjiang Province and the trend of change.MethodsThe incidence and mortality data of liver cancer in the cancer registration areas of Heilongjiang Province from 2013 to 2017 were collected, and the incidence(mortality) rate, age-standardized incidence(mortality) rate and cumulative rate(0-74 years old) were calculated. The ASR was calculated based on the Chinese population census in 2000(ASR China) and Segi′s world(ASR world) standard population. Annual percentage change(APC) was calculated by Joinpoint software.ResultsFrom 2013 to 2017, the incidence of liver cancer in the cancer registration areas of Heilongjiang Province was 29.13/105,the ASR China 17.18/10~5, and the cumulative rate(0-74 years old) 1.96%. The incidence of liver cancer in males(42.59/10~5) was higher than that in females(15.90/10~5), and the incidence of liver cancer in rural areas(35.05/10~5) was higher than that in urban areas(26.75/10~5). From 2013 to 2017, the mortality rate of liver cancer was 26.53/10~5, the ASR China 15.90/10~5, and the cumulative rate(0-74 years old) 1.78%. The mortality rate of liver cancer in males(38.33/10~5) was higher than that in females(14.93/10~5),and the mortality rate of liver cancer in rural areas(30.65/10~5) was higher than that in urban areas(24.88/10~5). From 2013 to2017, the ASR China incidence showed a downward trend, while ASR China mortality showed no significant trend(P>0.05), and the male ASR China incidence showed a significant downward trend(P<0.05).ConclusionsThe burden of liver cancer in Heilongjiang Province is relatively heavy, the incidence rate is decreasing, and the mortality is relatively stable. More attention should be paid to male and rural areas with comprehensive prevention and controlling measures.更多还原