【摘要】 目的探讨2013-2017年梅毒感染孕产妇及先天梅毒儿童的时间空间分布特征,进一步提高贵州省预防梅毒母婴传播干预效果。方法通过预防艾滋病、梅毒和乙肝母婴传播管理信息系统,收集2013-2017年贵州省梅毒感染孕产妇及所生儿童的相关信息,对梅毒感染孕产妇及先天梅毒儿童报告发病情况进行回顾性定量分析。结果 5年来,在对2 483 224例孕产妇的检测中,省内报告梅毒阳性孕产妇数为9550人,省外转入143人,以浙江省、云南省、广东省为主。2013-2017年期间,9个市(州)的梅毒阳性检测率分别是:铜仁市5.41‰、六盘水市4.90‰、黔南州4.56‰、毕节市3.79‰、安顺市3.66‰,为感染梅毒孕产妇疫情相对高发地区。全省孕产妇梅毒检测阳性数呈逐年增加趋势。感染梅毒孕产妇所生婴儿中先天梅毒儿童117例,2013-2017年期间,全省确诊先天梅毒儿童数逐渐上升。结论通过探讨梅毒感染孕产妇及先天梅毒儿童的时空分布特征,进而更好地估算全省孕产妇感染梅毒的趋势,评估孕产妇和先天梅毒儿童的防控效果,针对性对重点地区进行各级资金投入和督促落实梅毒母婴阻断干预措施,进一步提高贵州省预防梅毒母婴传播干预效果。更多还原

【Abstract】 Objective To explore the temporal and spatial distribution characteristics of syphilis-infected pregnant women and congenital syphilis children from 2013 to 2017, and to improve the effect of mother-to-child syphilis transmission blocking in Guizhou province.Method Adopting the management information system of mother-to-child transmission of HIV, syphilis and hepatitis B, to collect the information on syphilis-infected pregnant women and children born in Guizhou Province from 2013 to 2017, to do quantitative analysis on the incidence of syphilis infection in pregnant women and congenital syphilis.Result In the recent 5 years,2,483,224 pregnant women tested, within this group, the number of pregnant women reported positive of syphilis infection in Guizhou province was 9550, 143 cases were refer from Zhejiang, Yunnan and Guangdong Province. The syphilis positive rate from 2013 to 2017 in 5 cities of Guizhou were 5. 41‰ in Tongren City, 4. 90‰ in Liupanshui City, 4. 56‰ in Qiannan City, 3. 79‰ in Bijie city, and3. 66‰ in Anshun City respectively. These are relatively high-risk areas for pregnant women infected with syphilis. The positive number of maternal syphilis tests in the province showed an increasing trend year by year. There are 117 children of congenital syphilis born in pregnant women infected with syphilis. The number of children diagnosed with congenital syphilis increased gradually from 2013 to 2017 in province.Conclusion the trend in epidemics of maternal syphilis in the province would be estimated more exactly By exploring the temporal and spatial distribution characteristics of pregnant women infected with syphilis and the congenital syphilis cases,. By assessing the prevention and control effects of maternal and congenital syphilis, capital investment at all levels in the important areas and the measures of maternal and congenital syphilis prevention could be achieved. The blocking effect of mother-tochild syphilis transmission in Guizhou province would be further improved.更多还原