【摘要】 目的探讨临床药师参与国际临床照护计划认证(CCPC)模式对急性缺血性脑卒中药学服务效果的影响。方法选取黄石市中心医院2017年1月至2018年12月接受临床CCPC模式药学服务的急性缺血性脑卒中患者2 349例,比较临床药师介入CCPC模式照护团队开展药学干预前(2017年)、干预后(2018年)的临床药学服务效果。结果干预后,患者的药物治疗指南中"阿替普酶给药时机及剂量"治疗遵从度由44.30%升至96.69%(P <0.01),"抗血小板药物"治疗遵从度由58.87%升至96.35%(P <0.01),"他汀类药物"治疗遵从度由61.87%升至96.08%(P <0.01),用药总依从率由67.62%升至80.08%(P <0.05)。结论临床药师参与基于CCPC模式开展的药学服务,可显著提高药物治疗指南的遵从度及患者的用药依从率,可提升缺血性卒中单病种控制质量。更多还原

【Abstract】 Objective To investigate the effect of clinical pharmacists’ participation in the International Clinical Care Program Certification( CCPC) mode on pharmaceutical care of acute ischemic stroke. Methods A total of 2 349 patients with acute ischemic stroke who received pharmaceutical care based on CCPC mode in the Huangshi Central Hospital from January 2017 to December 2018 were selected,and the clinical pharmaceutical care effects before( in 2017) and after( in 2018) clinical pharmacists’ participation in the pharmaceutical care based on CCPC mode were compared. Results After the intervention,the adherence rate of ″timing and dose of alteplase″ in the drug treatment guidelines increased from 44. 30% to 96. 69%( P < 0. 01),the adherence rate of ″antiplatelet drugs″increased from 58. 87% to 96. 35%( P < 0. 01),the adherence rate of ″statins″ increased from 61. 87% to 96. 08%( P < 0. 01),and the total medication compliance rate increased from 67. 62% to 80. 08%( P < 0. 05). Conclusion The participation of clinical pharmacists in pharmaceutical care based on the CCPC mode can significantly improve the adherence of drug treatment guidelines and the medication compliance rate of patients,and improve the quality control of single disease of ischemic stroke.更多还原