【摘要】 目的探讨临床药师主导慢病管理对2型糖尿病患者治疗效果的影响。方法选取2018年1月—2019年12月河北医科大学第三医院就诊的132例2型糖尿病患者,按随机数字表法将其分为对照组(66例)与研究组(66例)。对照组采取传统医疗服务,研究组采取临床药师为主导的慢病管理服务。干预6个月,比较两组2型糖尿病主要指标控制情况。评估两组对药物了解程度及用药依从性。结果干预后两组空腹血糖、餐后2 h血糖、糖化血红蛋白、总胆固醇、低密度脂蛋白、收缩压、舒张压均低于干预前,且研究组低于对照组,差异均有统计学意义(均P <0.05)。干预后两组高密度脂蛋白水平均高于治疗前,且研究组高于对照组,差异有统计学意义(均P <0.05)。研究组对药物了解程度得分低于对照组,用药依从性评分高于对照组,差异均有统计学意义(均P <0.05)。结论临床药师主导慢病管理有助于改善2型糖尿病患者血糖、血脂和血压指标,以及提高其用药依从性。更多还原

【Abstract】 Objective To explore the influence of chronic disease management led by clinical pharmacists on the therapeutic effect of patients with diabetes mellitus type 2. Methods A total of 132 patients with diabetes mellitus type 2 admitted to the Third Hospital of Hebei Medical University from January 2018 to December 2019 were selected. According to random number table method, they were divided into control group(66 cases) and study group(66 cases).The control group was given traditional medical services, the study group was given chronic disease management services led by clinical pharmacists. The intervention lasted for six moths, the main indicators of diabetes mellitus type 2 control in the two groups was compared. Drug understanding and medication compliance of the two groups were evaluated. Results The levels of fasting blood glucose, two hours postprandial blood glucose, glycated hemoglobin, total cholesterol, low density lipoprotein, systolic blood pressure, and diastolic blood pressure in the two groups after intervention were lower than those before intervention, and those in the study group were lower than those in the control group, the differences were statistically significant(all P < 0.05). After intervention, high density lipoprotein levels in both groups were higher than those before treatment, and those in the study group were higher than those in the control group, with statistical significance(all P < 0.05). The score of drug understanding degree in the study group was lower than that in the control group, and the score of drug compliance was higher than that in the control group, with statistical significance(all P < 0.05). Conclusion Chronic disease management led by clinical pharmacists can improve blood glucose, lipid and blood pressure and medication compliance in patients with diabetes mellitus type 2.更多还原