【摘要】 目的研究妊娠高血压综合征的眼底病变与病情的关系。方法收集2018年3月-2019年10月天津市第一中心医院诊治的163例妊娠高血压综合征患者临床资料,均进行眼底检测,观察眼底病变程度与妊娠高血压综合征分期、平均动脉压水平、尿蛋白水平以及并发症的相关性以及妊娠高血压综合征预后与眼底病变的关系。结果妊娠高血压综合征患者眼底病变发生率为92.67%。不同分期、平均动脉压水平、蛋白尿水平妊娠高血压综合征患者眼底病变发生率比较,差异有统计学意义(P<0.05);眼底正常、Ⅰ期眼底病变妊娠高血压综合征患者早产发生率均低于Ⅱ期、Ⅲ期眼底病变者,差异有统计学意义(P<0.05);眼底正常、Ⅰ期眼底病变妊娠高血压综合征患者胎盘早剖、产后出血发生率均低于Ⅱ期、Ⅲ期眼底病变者,但差异无统计学意义(P>0.05);分娩结束后,妊娠高血压综合征患者眼底病变可逐渐恢复。结论妊娠高血压综合征眼底病变对其病情具有重要的预测价值,可通过动态观察眼底病变,了解妊娠高血压综合征患者分期、平均动脉压水平、尿蛋白水平以及并发症发生情况,为临床选择合适的干预措施和分娩方式提供参考依据,最大化确保母婴安全。更多还原

【Abstract】 Objective To study the relationship between fundus lesions and condition of pregnancy induced hypertension syndrome.Methods The clinical data of 163 patients with gestational hypertension syndrome treated in Tianjin First Central Hospital from March 2018 to October 2019 were collected. Fundus examination was performed to observe the correlation between the degree of fundus lesions and the stage of gestational hypertension syndrome, mean arterial pressure level, urinary protein level and complications, and the relationship between the prognosis of gestational hypertension syndrome and fundus lesions.Results The incidence of fundus lesions in patients with pregnancy induced hypertension syndrome was 92.67%. There were significant differences in the incidence of fundus lesions among patients with pregnancy induced hypertension syndrome at different stages, mean arterial pressure levels and proteinuria levels(P <0.05). The incidence of premature delivery in patients with normal fundus and stage Ⅰ fundus lesions was lower than that in patients with stage Ⅱ and stage Ⅲ fundus lesions, and the difference was statistically significant(P<0.05); while the incidences of placental early dissection and postpartum hemorrhage in patients with pregnancy induced hypertension syndrome with normal fundus and stage Ⅰ fundus lesions were lower than those in patients with stage Ⅱ and stage Ⅲ fundus lesions, but the difference was not statistically significant(P >0.05). After delivery, fundus lesions in patients with pregnancy-induced hypertension syndrome could gradually recover. Conclusion Fundus lesions of pregnancy induced hypertension syndrome have important predictive value for its condition. Through dynamic observation of fundus lesions,which can understand the stage, mean arterial pressure level, urinary protein level and complications of patients with pregnancy induced hypertension syndrome, so as to provide reference for clinical selection of appropriate intervention measures and delivery methods, and maximize the safety of mother and infant.更多还原