【摘要】 目的建立剖宫产预防用抗菌药物的药学临床路径,评价实施药学临床路径管理对降低产褥感染发生率、抗菌药物的使用强度、平均住院日等指标的效果。方法提取2018年某三级甲等妇幼保健院剖宫产术患者产褥感染的病例临床资料及其微生物培养结果,分析导致剖宫产患者术后发生产褥感染的高危因素及常见致病菌,制定该院剖宫产预防用抗菌药物的药学临床路径并在临床推广。以2018年剖宫产患者为对照组,2019年剖宫产患者为观察组,观察组按照新制定该院剖宫产预防用抗菌药物的药学临床路径进行管理。比较对照组和观察组患者产褥感染率、抗菌药物使用强度、平均住院日等住院指标,以评价实施药学临床路径管理的效果,使用χ2检验。结果对剖宫产患者预防用抗菌药物实施药学临床路径管理后,观察组产褥感染比例较对照组降低(P<0.05),抗菌药物的使用强度、平均住院日较对照组也有明显降低。结论实施剖宫产预防用抗菌药物药学临床路径管理,可显著降低剖宫产术后产褥感染发生比例,并能明显缩短平均住院日、有效提高医疗质量,值得在临床推广。更多还原

【Abstract】 Objective Establish the pharmacy clinical pathway of antibacterial drugs for the prevention of cesarean section, and evaluate the effect of the implementation of pharmacy clinical pathway management on reducing the incidence of puerperal infection, the intensity of antimicrobial use, and the average length of hospital stay. Methods To extract the clinical data and microbial culture results of cases of puerperal infection in patients undergoing cesarean section in a tertiary class A maternal and child health hospital in 2018, and analyze the high-risk factors and common pathogens that cause puerperal infection in cesarean section patients. Formulate the pharmacy clinical path of antibacterial drugs for the prevention of cesarean section in the hospital and promote it in the clinic. The 2018 ce-sarean section patients were used as the control group, and the 2019 cesarean section patients were used as the obser-vation group. The observation group was managed according to the newly formulated pharmacy clinical pathway of an-tibacterial drugs for caesarean section prevention in the hospital. Comparing the control group and the observation group patients’ rate of puerperal infection, antibacterial drug use intensity, average hospital stay and other hospital-ization indicators, to evaluate the effect of implementing pharmacy clinical pathway management. The chi-square test was used to correlate the classification data of the control group and the observation group. Results After the implementation of the pharmacy clinical pathway management of antibacterial drugs for the prevention of cesarean section patients, the proportion of puerperal infection in the observation group was significantly lower than that of the control group(P<0.05), and the intensity of antibacterial drug use and average hospital stay were also significantly lower than those of the control group. Conclusions The implementation of the pharmacy clinical pathway management of antibacterial drugs for the prevention of caesarean section can significantly reduce the incidence of puerperal infections after caesarean section, and can significantly shorten the average hospital stay and effectively improve the quality of medical treatment. It is worthy of clinical promotion.更多还原