【摘要】 胼胝体是人体最大的白质连接体,其能把两侧大脑半球的对应功能联系起来并协调成为一个整体。胼胝体缺失(ACC)是常见的胎儿中枢神经系统先天性发育畸形疾病,但是能生长发育至成年的ACC患者较为少见。我院于2019年12月22日收治1例因癫痫发作入院的成人ACC患者,该患者既往无特殊疾病史,家庭成员未患有与患者类似疾病,且否认家族性、遗传性病史;采用癫痫药物给予对症治疗后病情稳定。本文结合先天性ACC患者以及胼胝体切开术后患者的临床表现,通过分析两侧大脑半球之间的连接结构,探讨胼胝体功能缺失后的机体代偿机制和临床治疗方案。更多还原

【Abstract】 The corpus callosum is the largest white matter connectome in the human body, which can correlate and coordinate the corresponding functions of the two cerebral hemispheres into a whole. Agenesis of the corpus callosum(ACC) is a common congenital developmental malformation of the fetal central nervous system, but ACC patients who grow and develop into adulthood are relatively rare. Our hospital admitted 1 case of adult ACC patient caused by epileptic seizures on December 22, 2019. The patient had no history of special diseases, and no family members had similar diseases as the patient, so familial and hereditary medical history were denied; the condition of this patient is stable after symptomatic treatment with epilepsy drugs. Combining with the clinical manifestations of patients with congenital ACC and patients after corpus callosum incision, this paper explores the body compensation mechanism and clinical treatment after the loss of corpus callosum function through the analysis of the connection structure between the two cerebral hemispheres.更多还原