【摘要】 目的:探讨基于大矩阵重建PET图像在孤立性实性肺结节良恶性鉴别中的应用价值。方法:回顾性选取2019年12月-2021年3月在江门市中心医院接受治疗的孤立性实性肺结节患者80例作为研究对象。所有患者先进行常规PET/CT(128×128)图像检查,再将PET采集数据进行大矩阵(256×256)重建,测量结节的标准化摄取值(SUV)。对比两种重建方式图像质量及对肺结节良恶性诊断的差异。结果:大矩阵重建方式PET图像质量优于常规方式,差异有统计学意义(P<0.05);大矩阵重建方式良恶性显像的△SUV、延迟显像2 h SUVmax及常规显像1 h SUVmax值均高于常规方式(P<0.05)。病理诊断确诊为45例患者为良性结节,35例患者为恶性结节。大矩阵重建诊断准确率高于常规方式,误诊率、漏诊率低于常规方式,差异均有统计学意义(P<0.05)。结论:基于大矩阵重建PET图像可显著提高图像质量及在孤立性实性肺结节良恶性鉴别中的准确率,临床应用价值显著。更多还原

【Abstract】 Objective:To explore the application value of PET image reconstruction based on large matrix in differentiating benign and malignant solitary solid pulmonary nodules.Method:A total of 80 patients with solitary solid pulmonary nodules who were treated in Jiangmen Central Hospital from December 2019 to March 2021 were retrospectively selected as the research objects.All patients received routine PET/CT (128×128) image examination,then the PET data were processed with large matrix (256×256),the standardized uptake value (SUV) of nodules were measured.The image quality and differential diagnosis of benign and malignant pulmonary nodules were compared between the two reconstruction methods.Result:The large matrix reconstruction PET image had more excellent PET image quality than routine reconstruction,the difference was statistically significant (P<0.05);the values of △SUV,2 h SUVmax of delayed imaging and 1 h SUVmax of conventional imaging of large matrix reconstruction PET were higher than those of routine reconstruction (P<0.05).Pathological diagnosis confirmed that 45 patients were benign nodules,and 35 patients were malignant nodules.The diagnosis accuracy of large matrix reconstruction was higher than that of conventional method,and the misdiagnosis rate,missed diagnosis were lower than those of conventional method,the differences were statistically significant (P<0.05).Conclusion:PET image reconstruction based on large matrix can significantly improve the image quality and the accuracy in the differential diagnosis of benign and malignant solitary solid pulmonary nodules,and has significant clinical application value.更多还原