【摘要】 血液透析时抗凝治疗是其中的重要环节,抗凝过度或不足可致并发症或影响血透治疗效果。然而,目前未有明确血液透析抗凝相关的临床实用指南,也缺乏完整的抗凝选择的循证依据及临床实践报道。临床上抗凝方式多样,目前临床应用最广仍是普通肝素,其次是局部枸橼酸抗凝以及新型抗凝药阿加曲班。现就血液透析中的抗凝治疗现状及进展做一综述。更多还原

【Abstract】 Anticoagulant therapy is an important part of hemodialysis, and excessive or insufficient anticoagulation can lead to complications or affect the effect of hemodialysis therapy. However, there is no clear clinical practical guide on anticoagulation in hemodialysis, and there is also a lack of complete evidence-based medicine and clinical reports on anticoagulation selection. There are various anticoagulation methods in clinical practice. At present, unfractionated heparin is the most widely used for blood purification,followed by local citrate anticoagulation and new anticoagulant argatroban. This paper reviews the current situation and progress of anticoagulant therapy in hemodialysis.更多还原