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激光光凝联合康柏西普治疗增生型糖尿病视网膜病变的效果观察

Observation on the Effect of Laser Photocoagulation Combined with Conbercept in the Treatment of Proliferative Diabetic Retinopathy

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【作者】 李冰; 杨宾; 杨志理;

【Author】 LI Bing;YANG Bin;YANG Zhili;Department of Ophthalmology, the People’s Hospital of Nanzhao County;

【机构】 河南省南召县人民医院眼科;

【摘要】 目的探讨激光光凝联合康柏西普治疗增生型糖尿病视网膜病变(PDR)的临床效果。方法 80例PDR患者随机分为两组各40例,对照组采用激光光凝治疗,观察组在对照组基础上采用康柏西普治疗,比较两组的临床症状改善情况、临床疗效、黄斑区视网膜厚度。结果观察组的渗出吸收时间、眼底出血吸收时间、视网膜水肿改善时间均显著短于对照组,临床疗效显著优于对照组(P <0.05)。治疗后3个月,两组的黄斑区视网膜厚度均显著低于治疗前,且观察组显著低于对照组(P <0.05)。结论激光光凝联合康柏西普治疗PDR效果显著,可有效改善患者的临床症状,促进患者视网膜恢复。

【Abstract】 Objective To explore the clinical effect of laser photocoagulation combined with conbercept in the treatment of proliferative diabetic retinopathy(PDR). Methods 80 cases of PDR patients were randomly divided into two groups, with 40 cases in each group. The control group was treated with laser photocoagulation, while the observation group was treated with conbercept on the basis of the control group. The improvement of clinical symptoms, clinical efficacy and macular retinal thickness were compared between the two groups.Results The exudation absorption time, fundus hemorrhage absorption time and retinal edema improvement time in the observation group were significantly shorter than those in the control group, and the clinical efficacy was significantly better than that in the control group(P<0.05). 3 months after treatment, the macular retinal thicknesses in the two groups were significantly lower than those before treatment, and the observation group was significantly lower than the control group(P <0.05). Conclusions Laser photocoagulation combined with conbercept in the treatment of PDR has significant effect, and can effectively improve patients’ clinical symptoms, and promote the recovery of retina.

【基金】 河南省自然科学基金资助项目(1610004100818)
  • 【文献出处】 临床医学工程 ,Clinical Medicine & Engineering , 编辑部邮箱 ,2021年12期
  • 【分类号】R587.2;R774.1
  • 【被引频次】2
  • 【下载频次】40
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