【摘要】 自身免疫性甲状腺相关疾病与人类白细胞抗原(HLA)基因的关联性得到广泛临床关注。近年来,由于HLA分型技术的发展及对该类疾病发病机制认识的加深,一些新的疾病相关区域及位点被发现。本文对相关研究进行综述,以深入阐明该类疾病的病理过程和机制,为临床提供理论基础。更多还原

【Abstract】 The relation between autoimmune thyroid-related diseases and human leukocyte antigen( HLA) gene has attracted extensive clinical attention. In recent years,due to the development of HLA typing technology and the deepening understanding of the pathogenesis of this type of disease,several new disease-related regions and loci have been identified. In this paper,the relevant research progress was reviewed to further clarify the pathological process and mechanism of these diseases,and to provide a theoretical basis for clinical practice.更多还原