【摘要】 目的探讨创伤性脑损伤(TBI)病程及其严重程度对急性胃肠损伤(AGI)发生的影响。方法选取2018年7月至2019年7月重庆医科大学附属第一医院TBI患者182例,依据格拉斯哥昏迷量表(GCS)评分将TBI患者分为轻度组、中度组和重度组,评估不同时间点及不同脑损伤程度下AGI和胃肠道出血发生情况。结果 TBI后第1、3、7天均出现AGI和胃肠道出血,其中第3天AGI发生率明显高于第1、7天,第7天胃肠道出血发生率明显高于第1、3天,差异均有统计学意义(P<0.01)。TBI后第1、3、7天,重度组AGI发生率明显高于中度组和轻度组,且第3、7天胃肠道出血发生率明显高于中度组和轻度组,差异有统计学意义(P<0.01)。结论 TBI后第3天AGI发生率最高,且TBI越严重,AGI发生率越高。更多还原

【Abstract】 Objective To investigate the influence of the course and severity of traumatic brain injury(TBI)on the occurrence of acute gastrointestinal injury(AGI).Methods 182 patients with TBI in the First Affiliated Hospital of Chongqing Medical University from July 2018 to July 2019 were selected and divided into mild group,moderate group and severe group according to Glasgow Coma Scale(GCS)score.The incidence of AGI and gastrointestinal bleeding at different time points and different degrees of brain injury were evaluated.Results AGI and gastrointestinal bleeding occurred on the first,third and seventh days after TBI.The incidence of AGI on the third day was significantly higher than that on the first and seventh days,and the incidence of gastrointestinal bleeding on the seventh day was significantly higher than that on the first and third days(P<0.01).On the first,third and seventh days after TBI,the incidence of AGI in the severe group was significantly higher than that in the moderate group and the mild group,and the incidence of gastrointestinal bleeding on the third and seventh days was significantly higher than that in the moderate group and the mild group(P<0.01).Conclusion The incidence of AGI is the highest on the third day after TBI,and the TBI is more severe,the incidence of AGI is the higher.更多还原