【摘要】 太赫兹(Terahertz,THz)波具有相干性好、信噪比高、辐射能量低等性质,在传感领域有着广泛应用。此外,THz传感还具有实时、非接触、无标记、非电离等优点,在生化传感特别是生物活性物质的传感中有着重要应用。但THz传感也存在着灵敏度低、水的吸收强、检测信息有限、适用性差等缺陷。介绍在THz时域偏振光谱传感技术方面的系列工作,采用微结构器件作为传感器,使用透射或反射传感方法分别检测了细胞、氨基酸和脱氧核糖核酸(DNA)几种生化样品。实验结果表明:与传统的谐振传感方法相比,偏振传感方法的品质因数和传感灵敏度均有着显著提高;反射式传感有效避免了水对THz的吸收,实现了液体环境下活性生化样品的传感;使用具有手性的微结构器件作为传感器,或利用手性THz波作为激发场,可以增强样品的偏振响应,提高传感灵敏度,实现手性分子的传感。更多还原

【Abstract】 Terahertz(THz) waves have a wide range of applications in the field of sensing because of their good coherence, high signal-noise ratio, and low radiation energy. In addition, THz sensing also has the advantages of real-time, non-contact, label-free and non-ionization, so it has important applications in biochemical sensing, especially the sensing of biologically active substances. Nevertheless, THz sensing also has disadvantages such as low sensitivity, strong water absorption, limited detection information, and poor applicability. This review introduces the series of work of our research group in THz time-domain polarization spectroscopy sensing technology, which takes microstructure devices as sensors and uses transmission or reflection sensing methods to detect several biochemical samples of cells, amino acids and Deoxyribo Nucleic Acid(DNA), respectively. The experimental results show that: compared with the traditional resonance sensing method, the Q-factor and sensing sensitivity of the polarization sensing method are significantly improved; the reflective sensing effectively avoids the absorption of THz by water,and realizes the sensing of active biochemical samples in liquid environment; taking chiral microstructure devices as sensors, or taking chiral THz waves as excitation fields, the polarization response of the sample can be enhanced as well as the sensing sensitivity, and the sensing of chiral molecular is realized.更多还原