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降脂治疗中LDL-C水平目标值的探讨
Discussion of target value of LDL-C level in lipid-lowering therapy
【摘要】 血脂异常是动脉粥样硬化心血管疾病(ASCVD)的独立危险因素,降低低密度脂蛋白-胆固醇(LDL-C)水平,可显著降低ASCVD的发病率,但LDL-C的目标值应该是多少仍有争议。大多数研究证实,他汀类使LDL-C水平下降到调脂指南现有标准以下能使患者进一步受益,且降低至30mg/dl是安全的。因此,提倡在临床实践中,将LDL-C水平降低到现有指南推荐的水平以下。
【Abstract】 Dyslipidemia is an independent risk factor for atherosclerotic cardiovascular disease(ASCVD). Lowering level of low density lipoprotein-cholesterol(LDL-C) can significantly reduce morbidity of ASCVD, but the target value of LDL-C is still controversial. Most studies have confirmed that statins lower LDL-C level below the current standards of guidelines, which can further benefit patients. And it′s safe to reduce LDL-C to 30 mg/dl. Therefore, it is recommended to reduce LDL-C level to below the recommended level of existing guidelines in clinical practice.
- 【文献出处】 心血管康复医学杂志 ,Chinese Journal of Cardiovascular Rehabilitation Medicine , 编辑部邮箱 ,2021年01期
- 【分类号】R543.5
- 【被引频次】1
- 【下载频次】167