【摘要】 目的探究利伐沙班+奥扎格雷钠用于脑栓塞的效果及其对心理状态的影响。方法将2018年1月～2020年1月的60例脑栓塞患者根据分段随机化法进行分组,每组30例。对照组采用利伐沙班治疗,实验组则实施利伐沙班与奥扎格雷钠联合治疗。对两组治疗效果进行比较。结果实验组总有效率、日常生活活动能力量表(ADL)评分、格拉斯哥昏迷评分法(GCS)评分均高于对照组,P<0.05;实验组治疗后血小板计数(PLT)、血红蛋白(Hb)、活化部分凝血活酶时间(APTT)、凝血活酶时间(PT)等水平、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、不良事件发生率均低于对照组,P<0.05。结论脑栓塞患者接受利伐沙班与奥扎格雷钠联合治疗,安全有效。更多还原

【Abstract】 Objective To explore the effect of rivaroxaban + ozargrel sodium on cerebral embolism and its effect on psychological state. Methods A total of 60 patients with cerebral embolism were randomly divided into two groups: the control group received rivaroxaban treatment, and the experimental group received rivaroxaban combined with ozagrel sodium treatment. Results The total effective rate, activities of daily living scale(ADL) and Glasgow coma scale(GCS) of the experimental group were higher than those of the control group, P<0.05. After treatment, platelet count(PLT), hemoglobin(Hb), activated partial thromboplastin time(APTT), thromboplastin time(PT), self-rating anxiety scale(SAS) score, self-rating depression scale(SDS) score and incidence of adverse events in the experimental group were lower than those in the control group, P<0.05. Conclusion The combined treatment of rivaroxaban and ozagrel sodium is safe and effective in patients with cerebral embolism.更多还原