【摘要】 目的对精神心理因素与反流性食管炎之间存在的关系,包括抗抑郁治疗的临床效果进行探讨、分析和论述。方法采取汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)对186例反流性食管炎患者进行综合评分,观察常规治疗会对HAMA、HAMD评分产生怎样的影响。按门诊时间的先后将被试均分成两组,给予对照组常规治疗,实验组在对照组常规治疗的基础上加用疏肝健脾汤,对比分析两组患者的症状改善程度以及HAMA与HAMD评分变化情况。结果相对于同期在本院进行健康体检的正常人群来说,反流性食管炎患者无论是在抑郁症发生率方面还是在焦虑症发生率方面,都明显要高出许多;对照组在接受常规治疗后,HAMA和HAMD的评分都出现了下降的趋势;在疏肝健脾汤用药的辅助作用下,实验组的HAMA和HAMD评分的下降幅度都要比对照组更加明显(P<0.05)。结论在临床诊治反流性食管炎患者的实际过程中,发现其精神心理因素和该疾病有着十分紧密的联系性,采取抗抑郁治疗的方式有助于反流性食管炎治疗效果的进一步提高,因此,这种方法值得在当代临床中进行大范围普及、推广与应用。更多还原

【Abstract】 Objective To discuss,analyze and discuss the relationship between mental and psychological factors and reflux esophagitis,including the clinical effects of antidepressant treatment.Methods The Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD) were used to comprehensively score 186 reflux esophagitis patients to observe the effect of conventional treatment on HAMA and HAMD scores.The subjects were divided into two groups according to the outpatient time.The control group was given conventional treatment.The experimental group was treated with Shugan Jianpi decoction on the basis of the conventional treatment of the control group.The symptom improvement of the two groups was compared and analyzed,as well as HAMA and HAMD changes in the score.Results Compared with the normal population who underwent physical examination in this hospital during the same period,patients with reflux esophagitis were significantly higher in both the incidence of depression and anxiety;the control group was receiving routine after treatment,the scores of HAMA and HAMD showed a downward trend;with the auxiliary effect of Shugan Jianpi decoction,the decline of HAMA and HAMD scores of the experimental group was more obvious than that of the control group (P<0.05).Conclusion In the actual process of clinical diagnosis and treatment of patients with reflux esophagitis,it is found that their mental and psychological factors are very closely related to the disease.Taking antidepressant treatment will help to further improve the treatment effect of reflux esophagitis.Therefore,this method is worthy of widespread popularization,promotion and application in contemporary clinics.更多还原