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广东地区男性生育力保存肿瘤患者来源分析

Source analysis of fertility preservation of male cancer patients in Guangdong

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【作者】 叶桂芳舒小妹罗璐璐林维新伍欣钟恺欣王奇玲

【Author】 YE Guifang;SHU Xiaomei;LUO Lulu;LIN Weixin;WU Xin;ZHONG Kaixin;WANG Qiling;NHC Key Laboratory of Male Reproduction and Genetics;Department of Andrology,Guangdong Provincial Reproductive Science Institute;Human Sperm Bank,Guangdong Provincial Fertility Hospital;Department of Nursing,Guangdong Provincial Fertility Hospital;

【通讯作者】 王奇玲;

【机构】 国家卫生健康委员会男性生殖与遗传重点实验室广东省生殖科学研究所男科广东省生殖医院人类精子库广东省生殖医院护理部

【摘要】 目的分析广东地区实施男性生育力保存的肿瘤患者的来源,为我国人类精子库拓展男性肿瘤患者的生育力保存服务提供参考。方法选取2017年—2020年广东省生殖医院人类精子库接收的252例进行生育力保存的男性肿瘤患者相关信息进行回顾性分析。按肿瘤类型、地区来源及推荐生育力保存的医院规模等进行分组,分析不同肿瘤类型、地区来源、医院分布等指标。结果 252例男性肿瘤患者中,以淋巴瘤、睾丸肿瘤、鼻咽癌、肠道癌和白血病为主,占84.52%;患者所在地区主要分布在广东省珠三角地区,其中广州最多,为84.92%,广东省内其他地区患者仅占1.98%;推荐生育力保存的医院主要来自三级甲等肿瘤综合性医院、三级甲等综合性医院,分别占48.41%及46.03%,剩余5.56%来自其他医院,如二级甲等医院或民营医院等。结论我国男性肿瘤患者生育力保存的比例极低,应加强生育力保存相关医疗知识的宣传,提高相关科室医生对生育力保存的认知;提供快捷的生育力保存途径,针对经济特别困难的患者减免一定的保存费用,最大限度提升我国男性肿瘤患者生育力保存的比例,使更多育龄男性肿瘤患者拥有自己的生物学子代。

【Abstract】 Objective To analyze the source of fertility preservation of male cancer patients in Guangdong, and provide suggestions for expanding the fertility preservation service of male tumor patients in China′s human sperm bank. Methods Data of 252 male tumor patients with fertility preservation received from Human Sperm Bank, Guangdong Provincial Fertility Hospital from 2017 to 2020 were retrospectively analyzed. They were grouped by tumor type, regional origin, and hospital scale recommended for fertility preservation. Results Among 252 male tumor patients, lymphoma, testicular tumor, nasopharyngeal cancer, leukemia and intestinal cancer were dominant, accounting for 84.52%. The cases were mainly distributed in the Pearl River Delta region of Guangdong Province, with 84.92% in Guangzhou, and only 1.98% in other regions of Guangdong province. The hospitals recommended for fertility preservation mainly came from grade Ⅲ level-A affiliated tumor hospitals and grade Ⅲ level-A general hospitals, accounting for 48.41% and 46.03% respectively, and the rest 5.56% came from other hospitals, such as Grade Ⅱ levle-A hospitals or private hospitals. Conclusions The proportion of fertility preservation of male cancer patients in China is very low. We should strengthen the publicity of medical knowledge related to fertility preservation and improve the doctors′ cognition of fertility preservation; provide a fast way of fertility preservation and reduce certain preservation costs for patients with special economic difficulties, so as to maximize the proportion of fertility preservation of male tumor patients in China, so that more male tumor patients of childbearing age have their own biological children.

【关键词】 生育力保存肿瘤育龄男性
【Key words】 Fertility preservationTumorMale of childbearing age
【基金】 广州市科技计划项目(202002030480);广东省自然科学基金(2021A1515011544);广东省计划生育科学技术研究所创新团队培育计划项目(C01);广东省医学科研基金(B2020077)
  • 【文献出处】 中国性科学 ,Chinese Journal of Human Sexuality , 编辑部邮箱 ,2021年11期
  • 【分类号】R730
  • 【下载频次】123
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