【摘要】 目的体外模拟532 nm激光通过多焦点人工晶状体(MIOL)进行光凝,比较激光通过MIOL和单焦点IOL进行光凝时产生的激光斑差异,为临床MIOL植入术后患者的眼底激光治疗提供理论依据。方法根据IOL的不同分为三组,A组为对照组,应用单焦点IOL;B组与C组分别应用区域折射型MIOL和衍射型MIOL。采用化学涂层热敏纸模拟人眼视网膜。在无IOL的条件下进行光凝,参考人眼视网膜激光斑的分级标准将热敏纸激光斑分为Ⅰ～Ⅳ级。应用532 nm激光通过三组IOL进行光凝,比较三组间各级激光斑数量。若三组的激光斑分布存在差异,则逐步提高激光斑分级较低一组的激光功率后再比较。结果在相同激光功率条件下,三组的各级激光斑数量比较,差异有统计学意义(P<0.05)。两两比较结果显示,C组与A组激光斑数量差异均有统计学意义(均为P<0.05),B组与A组激光斑数量差异均无统计学意义(均为P>0.05)。少量提高C组的激光功率后再次与A组比较,各级激光斑数量差异均无统计学意义(均为P>0.05)。结论应用532 nm激光进行激光光凝时,衍射型MIOL对激光斑有一定影响,但少量提高激光功率后,也可以达到单焦点IOL在原激光功率下的效果。通过区域折射型MIOL进行光凝与单焦点IOL相比无明显差异。更多还原

【Abstract】 Objective To simulate the process of photocoagulation with 532 nm laser through multifocal intraocular lens(MIOL) in vitro, and observe the difference of light spots formed by laser through MIOL and monofocal intraocular lens(IOL), so as to provide a theoretical basis for fundus laser treatment of patients receiving MIOL implantation.Methods The patients were divided into groups A, B and C according to different intraocular lens(IOL). The group A was control group which was treated with monofocal IOL. Group B and group C were respectively treated with regional refractive MIOL and diffractive MIOL. Chemically coated thermal paper was used to simulate human retina. Firstly, photocoagulation was performed without IOLs. These laser spots were classified into Ⅰ to Ⅳ levels based on the grading standard of laser spots in human retina. Then photocoagulation with 532 nm laser was performed in A, B and C groups, and the numbers of laser spots in the three groups were compared. If the distribution of laser spots were different, laser power of the group with the lowest spot level would be increased gradually and then the laser spots would be compared again. Results Under the same laser power, the distribution of spots in 3 groups were significantly difference(P<0.05). Pairwise comparison showed that the difference between group C and group A had statistical significance(all P<0.05), and there was no statistical significance of the difference between group B and group A(all P>0.05). After slightly increase of the laser power of group C, the laser spots in the four levels showed no significant difference with group A(all P>0.05).Conclusion With the application of 532 nm laser to photocoagulation, diffractive MIOL has a certain effect on laser spots. After a slight increase of laser power, it can also reach the effect of monofocal IOL under the original laser power. There was no significant difference between regional refractive MIOL and monofocal IOL in photocoagulation.更多还原