【摘要】 目的总结面部化妆品接触性皮炎发病特点,探索斑贴试验在面部化妆品接触性皮炎患者中的临床意义。方法收集患者一般资料、问题化妆品信息并进行斑贴实验,对收集的数据进行描述性统计。结果 (1)376例面部化妆品接触性皮炎患者中以女性居多,占97.61%,年龄中位数为32岁。88.56%的患者发生在16岁～56岁,21岁～30岁最多,占35.48%。79.26%的患者3d内发病,皮损形态以红斑、丘疹为主,自觉症状瘙痒、灼热、干燥为主。(2)国产问题化妆品多于进口的:普通类型均以面膜类最多;特殊用途类问题化妆品中,国产问题化妆品以染发类较多,进口的以防晒类较多。(3)105例患者进行标准斑贴试验,阳性率为70.47%,以硫柳汞和硫酸镍过敏的最多。原物斑贴阳性率为24.24%。结论通过临床数据及斑贴实验结果分析,总结本地区面部化妆品接触性皮炎患者发病的特点,辅助临床诊断,指导消费者正确购买和使用化妆品,减少面部化妆品接触性皮炎的发生。更多还原

【Abstract】 Objective To summarize the pathogenesis of facial cosmetic contact dermatitis and explore the clinical significance of patch test in patients with facial cosmetic contact dermatitis. Methods Facial cosmetic contact dermatitis patients’ general information and information on problematic cosmetic were collected. 105 patients performed patch tests. Descriptive statistics were performed on the collected data. Results(1)Among the 376 patients with facial cosmetic contact dermatitis, women were the most, which accounting for 97.61%, and the median age was 32 years. 88.56% of patients occurred between 16 and 56, with the largest number of patients aged between 21 and 30, which accounting for 35.48%. 79.26% of patients developed symptoms within 3 days. Skin lesions included erythema and papules, and main symptoms were itching, burning, and dryness.(2)There were more domestic than imported problematic cosmetics.facial masks were the most in common problematic cosmetics. Hair dyeing products in domestic products and sunscreen products in imported products were problematic in special-purpose suspicious cosmetics.(3)105 patients underwent standard patch tests, the positive rate was 70.47%. Thimerosal and nickel sulfate allergic were the most common in patients. The positive rate of the original patch tests was 24.24%. Conclusion Based on the analysis of clinical data and patch test results, the characteristics of patients with contact dermatitis of facial cosmetics are summarized, it would be assisted in clinical diagnosis for doctor and guide consumers to purchase and use cosmetics correctly, and finally reduce the occurrence of contact dermatitis of facial cosmetics.更多还原