【摘要】 目的调查卵巢癌化疗患者症状群与舒适状况的现状及相关性。方法采用便利抽样法,选取2019年6月～12月我院卵巢癌住院患者230例,采用一般资料调查表、中文版安德森症状评估表和简化舒适状况量表进行调查。结果卵巢癌化疗患者症状频率前3位为恶心(86.09%)、食欲不振(81.73%)和苦恼(76.52%),症状严重程度前3位为疲乏(5.28分)、恶心(4.28分)和食欲不振(4.17分)。探索性因子分析提取出4个症状群,分别为情绪症状群、疾病症状群、疲乏症状群和胃肠道症状群。4个症状群与舒适状况呈负相关(r=-0.411～-0.671,P<0.05),多元线性回归分析显示胃肠道症状群和疲乏症状群进入舒适状况回归方程,共解释53.50%的变异度。结论卵巢癌化疗患者存在多个症状群,临床医护人员应从症状群的角度出发,为患者提供有效的症状管理措施,提高其舒适度。更多还原

【Abstract】 Objective To investigate the status and correlation between symptom cluster and comfort of patients with ovarian cancer undergoing chemotherapy. Methods The convenient sampling method was designed to investigate 230 inpatients with ovarian cancer undergoing chemotherapy in a third grade a special hospital in Chengdu from June to December 2019. The General Information Questionnaire, Chinese version of M. D. Anderson Symptom Inventory(MDASI) and General Comfort Questionnaire(GCQ) were used to investigate. Results The top 3 symptoms in terms of frequency in ovarian cancer patients treated with chemotherapy were nausea(86.09%), loss of appetite(81.73%) and distress(76.52%), while the top 3 symptoms in terms of severity were fatigue(5.28), nausea(4.28) and loss of appetite(4.17). Four symptom clusters were extracted by exploratory factor analysis, namely emotional symptom cluster, disease symptom cluster, fatigue symptom cluster and gastrointestinal symptom cluster. Four symptom clusters were negatively correlated with comfort(r=-0.411～-0.671, P<0.05). Multiple linear regression analysis showed that gastrointestinal symptom cluster and fatigue symptom cluster entered the comfort state regression equation, accounting for 53.50% of the variance. Conclusion There are many symptom clusters in ovarian cancer patients undergoing chemotherapy. Clinical nurses should start from the point of view of symptom cluster, and provide effective symptoms management measures for patients, to improve their comfort.更多还原