【摘要】 目的:探讨吸烟对青年女性冠心病患者冠状动脉病变程度及介入治疗的影响。方法:回顾分析2007年1月至2017年6月期间,行冠状动脉造影检查的青年女性患者870例(年龄≤44岁)。依据患者是否吸烟分为吸烟组(n=41)和对照组(n=829)。两组基线资料比较差异无统计学意义(P>0.05)。本组青年女性的吸烟率为4.7%(41/870)。观察两组中冠心病患者的冠状动脉病变程度和介入治疗的情况。结果:吸烟组冠心病介入治疗为70.7%(29/41),对照组为50.8%(421/829),两组比较差异有统计学意义(P<0.05)。两组血管病变分布差异无统计学意义(P>0.05),B1和B2型病变的分布在两组差异无统计学意义(P>0.05)。但吸烟组中A型病变显著少于对照组(P<0.05),C型病变显著多于对照组(P<0.05)。吸烟组冠心病介入治疗患者置入支架的数量和长度分别为3.00 (2.00,3.00)个和(28.03±6.49)mm,均大于对照组置入支架的数量1.00 (1.00,2.00)个和长度(23.63±6.89) mm,组间比较差异有统计学意义(P<0.05)。结论:吸烟促进青年女性冠心病患者发病和使冠状动脉病变程度加重。应积极防控吸烟,降低冠心病的患病率。更多还原

【Abstract】 Objective: To investigate the effect of smoking on the severity of coronary artery lesions and stenting in young women with coronary artery disease. Methods: A retrospective analysis was performed on 870 young female patients(age ≤44 years) who underwent coronary angiography from January 2007 to June 2017. Patients were divided into smoking group(n=41) and control group(n=829) based on whether they smoked or not. There was no significant difference in the baseline data between the two groups(P>0.05). The smoking rate of young women in this study was 4.7%(41/780). The severity of coronary artery lesions and stenting in patients with coronary artery disease in both groups were observed. Results: The coronary intervention was 70.7%(29/41) in the smoking group and 50.8%(421/829) in the control group, with a statistically significant difference between the two groups(P<0.05). There was no significant difference in the distribution of vascular lesions between the two groups(P>0.05), and the distribution of type B1 and B2 lesions was not significantly different in the two groups(P>0.05). However, there were significantly fewer type A lesions in the smoking group than in the control group(P<0.05) and significantly more type C lesions than in the control group(P<0.05). The number and length of stents implanted in patients with coronary interventions in the smoking group were 3.00(2.00,3.00) and(28.03±6.49)mm, respectively, which were greater than the number of stents implanted in the control group, which were 1.00(1.00,2.00) and(23.63±6.89)mm, and the difference between groups was statistically significant(P<0.05). Conclusions: Smoking promotes the onset and exacerbates the degree of coronary lesions in young women with coronary artery disease. Smoking should be actively prevented and controlled to reduce the prevalence of coronary artery disease.更多还原