【摘要】 目的探讨不同握球时长对置入耐高压双腔PICC导管鼻咽癌患者握球依从性的影响,以期为临床提供一种安全有效的握球运动。方法采用便利取样法,选择2019年8月—2020年6月在佛山市第一人民医院肿瘤中心首次行超声下上臂置入耐高压双腔PICC导管化疗的鼻咽癌患者134例,按照随机数字表法将患者随机分为试验组66例和对照组68例。试验组采用2s的主动握球运动,对照组采用10s的主动握球运动,比较两组患者置管后7d、1个月、3个月导管相关性血栓(catheter related thrombosis,CRT)、机械性静脉炎、导管移位发生率及依从性的差异。结果两组患者置管后7d、1个月、3个月新发症状性CRT、机械性静脉炎和导管移位发生率比较,差异无统计学意义(均P>0.05);而试验组在置管术后7d及3个月依从性高于对照组,组间比较,差异有统计学意义(χ2值分别为4.660、4.238, P值分别为0.031、0.040)。结论与10s握球运动相比,2s握球运动未增加耐高压双腔PICC导管相关性血栓、导管移位和机械性静脉炎的发生率,但可提高患者握球依从性。更多还原

【Abstract】 Objective To investigate the impact of different duration of balloon squeezing on the compliance of nasopharyngeal carcinoma patients with high-pressure-resistant double-cavity peripherally inserted central catheter(PICC) for the purpose of providing an effective and safe balloon-squeezing exercise in clinical practice. Methods Data of 134 nasopharyngeal carcinoma patients with high-pressure-resistant double-cavity PICC were collected from the Cancer Centre of Foshan First People ’s Hospital between August 2019 and June 2020. Patients were divided into trial group(n=66) and control group(n=68) according to the random number table. The trial group and control group were asked to complete a balloon squeezing exercise for 2 seconds and 10 seconds, respectively. Chi-square test was used to compare the differences in the incidence of catheter-related thrombosis(CRT),mechanical phlebitis, catheter displacement and compliance between the two groups at the time points of 7 days, 1 month, and 3 months after catheterisation. Results There were no statistically significant differences between the two groups in terms of the incidence of new symptomatic CRT, mechanical phlebitis and catheter displacement at the three time points(P >0.05), but the compliance of the trial group was significantly higher than that in the control group at the time points of 7 days and 3 months after catheterisation( χ2= 4.660, 4.238; P=0.031,0.040, respectively). Conclusions Compared with the balloon squeezing exercise for 10 seconds, the 2 seconds balloon squeezing exercise does not increase the incidence of CRT, catheter displacement and mechanical phlebitis, but improve the gripping compliance in patients. Further multi-centre and large sample size studies are necessary to confirm its clinical value.更多还原