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胸痛中心模式对STEMI患者急诊PCI救治效率、效果及心肌损伤、生活质量的影响

Effect of chest pain center model on emergency PCI treatment efficiency, effect, myocardial injury and quality of life in patients with STEMI

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【作者】 孙红梅徐冬梅张新月李娟王骁智戴振华

【Author】 SUN Hong-mei;XU Dong-mei;ZHANG Xin-yue;LI Juan;WANG Xiao-zhi;DAI Zhen-hua;Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People’s Hospital);

【通讯作者】 徐冬梅;

【机构】 南京医科大学第一附属医院(江苏省人民医院)心血管内科

【摘要】 【目的】研究胸痛中心模式对ST段抬高型心肌梗死(STEMI)患者急诊经皮冠状动脉介入(PCI)救治效率、效果及心肌损伤、生活质量的影响。【方法】选择2018年4月至2020年1月胸痛中心成立后收治的STEMI患者作为观察组,另取2016年1月至2018年3月胸痛中心成立前收治的STEMI患者作为对照组,均接受急诊PCI。观察两组患者的救治效率、效果及PCI后心肌损伤标志物峰值含量及生活质量评分。【结果】观察组的首次医疗接触-球囊扩张(FMC2B)时间、进医院大门-球囊扩张(D2B)时间、急诊室停留时间、首份心电图确诊时间均明显短于对照组,院内心衰、恶性心律失常、死亡的发生率以及PCI术后6个月内心血管死亡、再发心肌梗死的发生率均明显低于对照组(P<0.05),PCI术后72 h内磷酸肌酸激酶同工酶(CK-MB)、肌钙蛋白I(cTnI)峰值含量明显低于对照组(P<0.05),两组的医学结局研究简短量表-8(SF-8)、西雅图心绞痛量表(SAQ)评分在出院时无明显差异,而在出院后6个月观察组的SF-8、SAQ评分均高于对照组(P<0.05)。【结论】胸痛中心模式用于STEMI患者急诊PCI能够提高救治效率,改善救治效果,减轻心肌损伤及提高出院后生活质量。

【Abstract】 【Objective】To study the effects of chest pain center model on the efficiency, effect, myocardial injury and quality of life of emergency percutaneous coronary intervention(PCI) in patients with ST segment elevation myocardial infarction(STEMI). 【Methods】STEMI patients admitted after the establishment of the chest pain center from April 2018 to January 2020 were selected as the observation group, and STEMI patients admitted before the establishment of the chest pain center from January 2016 to March 2018 were selected as the control group, all of whom received emergency PCI. The treatment efficiency, effect, peak content of myocardial injury markers and quality of life score after PCI were observed. 【Results】The first medical contact to balloon(FMC2B) time, door to baloon(D2B) time, emergency room stay time and the first ECG diagnosis time in the observation group were significantly shorter than those in the control group. The incidence of in-hospital heart failure, malignant arrhythmia and death, as well as the incidence of cardiovascular death and recurrent myocardial infarction 6 months after PCI were significantly lower than those in the control group(P<0.05). The peak contents of cardia troponin I(cTnI) and creatine kinaseisozyme(CK-MB) within 72 hours after PCI were significantly lower than those in the control group(P<0.05), there was no significant difference in the scores of short scale-8(SF-8) and Seattle angina questionnaire(SAQ) between the two groups at discharge, but the scores of SF-8 and SAQ in the observation group were higher than those in the control group 6 months after discharge(P<0.05). 【Conclusion】Chest pain center mode for emergency PCI of STEMI patients can improve the treatment efficiency, improve the treatment effect, reduce myocardial injury and improve the quality of life after discharge.

  • 【文献出处】 武警后勤学院学报(医学版) ,Journal of Logistics University of PAP(Medical Sciences) , 编辑部邮箱 ,2021年12期
  • 【分类号】R542.22
  • 【下载频次】32
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