【摘要】 目的骨化性气管支气管病(tracheobronchopathia steochondroplastiesa,TO)是临床少见疾病,本研究旨在提高临床医师对TO的认识。方法对收治的1例TO病例的临床资料进行分析,并结合文献复习TO的临床特点、诊断要点及相关治疗。结果 TO临床表现无特异性。胸部CT表现为气管壁不规则增厚或钙化结节突向管腔。支气管镜下可见气管前壁和侧壁多发的孤立性或融合的结节,不累及气管膜部。病理学检查可见气管、支气管黏膜下软骨和骨性结节形成。结论 CT是TO重要的非侵入性诊断方法 ,支气管镜检查具有特征性,组织病理学检查对TO具有进一步确诊的作用。更多还原

【Abstract】 Objective Tracheobronchopathia osteochondroplastica(TO) is a rare clinical disease. The study aims to improve clinicians′ understanding of TO. Methods The clinical data of a patient with TO were analyzed,the clinical features,diagnosis,and treatment of TO were discussed combining with literature. Results The clinical manifestations of TO were not specific. Chest CT scanning showed irregular thickening and calcified nodularties protruding into the tracheobronchial lumen. Bronchoscopy showed that the anterior and lateral walls of the tracheal were widely multiple solitaries or fused small cobblestone nodular protrusion,without the involvement of the posterior membrane. Histopathologic examination of the biopsied tissue showed cartilage and bone nodules under the mucosa of the trachea and bronchus. Conclusion High-resolution CT is an important non-invasive method for the diagnosis of TO. There are characteristic presentations under bronchoscope. Histopathological examination is a further confirmation of the diagnosis.更多还原