【摘要】 原发性肝癌在中国的发生率及死亡率多年以来一直稳居恶性肿瘤的前五位,且复发率高,预后不良。近些年,随着人们对基因表达与癌症发生发展相关研究的不断深入,探索范围已不仅仅局限于编码RNA的研究,许多非编码RNA在恶性肿瘤进展过程中的作用也逐步引起了研究者们的重视,其中RNA结合蛋白作为参与这些RNA调控的"交通枢纽"起到了至关重要的作用。本文将针对肝细胞癌相关的RNA结合蛋白研究进展进行阐述,旨在为今后的研究提供有价值的参考及思路。更多还原

【Abstract】 The incidence and mortality of primary liver cancer in China have been among the top five malignant tumors for many years, the recurrence rate is high and the prognosis is poor.In recent years, with the continuous in-depth research on gene expression, carcinogenesis and development, the scope of exploration is not limited to the study of coding RNA.Many non-coding RNAs have been gradually attracted the attention of researchers.RNA binding proteins, as the“transportation hub”involved in the regulation of these RNAs, play an important role.This article will describe the research progress of RNA-binding proteins related to hepatocellular carcinoma one by one, in order to provide valuable references and ideas for future research.更多还原