【摘要】 肿瘤微环境(Tumor microenvironment, TME)在肿瘤的发生发展中发挥重要作用。应激状态下的人体通常会经历一些重要的生物效应,从而损害免疫系统,各种应激反应可以通过调节肿瘤微环境中的免疫细胞,例如自然杀伤细胞、树突状细胞、髓系来源抑制细胞(MDSCs)等,导致肿瘤进展。由于免疫细胞对人体的多项活动都起着重要的调节作用,并且其在肿瘤中的应用也具有十分重要的意义。本文就心理应激如何影响肿瘤微环境中的免疫细胞做一综述,旨在为肿瘤治疗提供新的思路。更多还原

【Abstract】 Tumor microenvironment(TME)plays an important role in the occurrence and development of tumors.The human body under stress usually undergoes some important biological effects, which impair the immune system.Various stress responses can regulate immune cells in TME,such as natural killer cells, dendritic cells, and myeloid-derived suppressive cells(MDSCs),etc.the responses lead to tumor progression.Because immune cells play an important role in regulating multiple activities of human body and their application in tumors is also of great significance.This article reviews how psychological stress affects immune cells in TME in order to provide new ideas for tumor therapy.更多还原