【摘要】 目的 :探讨重建肠道微生态疗法对肠易激综合征患者T淋巴细胞亚群的影响。方法 :选取100例肠易激综合征患者随机分为对照组和研究组各50例,对照组予以匹维溴铵对症治疗4周,研究组实施重建肠道微生态疗法治疗1周,于治疗前和治疗后1个月测定外周血T淋巴细胞亚群计数及比值。结果 :治疗前两组T淋巴细胞亚群计数及比值无显著差异。治疗后,研究组的CD4~+值、CD4~+/CD8~+值较前升高,CD8~+值较前下降,且CD4~+值显著高于对照组,CD8~+值显著低于对照组,差异有统计学意义。结论 :重建肠道微生态疗法可有效改善肠易激综合征患者的外周血T淋巴细胞亚群比例。更多还原

【Abstract】 Objective: To investigate the effect of intestinal microecotherapy on T lymphocyte subsets in patients with irritable bowel syndrome. Methods: One hundred patients with irritable bowel syndrome were randomly divided into a control group and a study group with 50 cases each. The control group was treated with pinaverium bromide for four weeks, while the study group was treated with remodeling intestinal microecology for one week. The T lymphocyte subsets and their ratios were measured before and one month after treatment. Results: There were no significant differences in T lymphocyte subsets count and ratio between the two groups before treatment. After treatment, the CD4~+ value and CD4~+/CD8~+ value increased and the CD8~+ value decreased in the study group, and furthermore the CD4~+ value was significantly higher and the CD8~+ value was significantly lower in the study group than the control group(P<0.05). Conclusion: Reconstruction of intestinal microecology therapy can effectively improve the proportion of T lymphocyte subsets in patients with irritable bowel syndrome.更多还原