【摘要】 目的分析内镜下全层切除术(EFTR)治疗十二指肠非乳头区黏膜下病变的疗效和安全性。方法回顾性统计本中心从2012年2月至2020年1月治疗的102例十二指肠非乳头区黏膜下病变行EFTR治疗的患者,探讨分析手术创面缝合方式、术中术后并发症情况、围手术期处理、肿瘤特点和病理结果等。结果病灶完整切除率为100%;除了2例中转外科手术外,所有患者均成功接受EFTR手术。1例患者术后出现严重腹痛,考虑迟发性穿孔,并行腹腔镜探查。1例患者因迟发性出血接受急诊内镜治疗。1例患者术后氧饱和度下降,转入重症监护室进一步对症治疗。其余患者未发现瘘等其他并发症,所有患者均成功治愈。结论对于十二指肠非乳头区黏膜下病变,EFTR术安全、微创,切除病灶完全,值得临床进一步推广应用。更多还原

【Abstract】 Objective To study the efficacy and safety of the endoscopic full-thickness resection(EFTR) for non-ampullary duodenal subepithelial lesions. Methods We retrospectively analyzed 102 patients with non-ampullary duodenal subepithelial lesions who underwent EFTR between February 2012 and January 2020.The suturing method,complications that occurred during and after the operations,perioperative management, tumor characteristics, and pathological findings were analyzed in all patients. Results The completere section rate was 100%. All patients successfully received EFTR except for 2 patients who required conversion to surgery. Severe abdominal pain was observed after the operation in one patient who then received laparoscopic exploration, and the possibility of delayed perforation was considered. One patient suffered delayed bleeding and received emergent endoscopic treatment. Another patient showed a decline in blood oxygen saturation and then was transferred to the intensive care unit for further management. Fistula and other complications were not observed. All patients achieved complete remission. Conclusion EFTR is a safe and minimally invasive treatment modality that ensures complete eradication of the duodenal subepithelial lesions.更多还原