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荷叶方中药酵素体外降血脂活性研究

Study on in vitro Hypolipidemic Activity of Chinese Herb Enzyme of Lotus Leaf Prescription

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【作者】 惠洁张存莉

【Author】 HUI Jie;ZHANG Cunli;College of Chemistry & Pharmacy, Northwest A&F University;Hanzhong Key Research and Testing Laboratory for Edible Plant-source Jiaosu, Shaanxi Wuding Biotechnology Co.,Ltd.;Yan’an vocational & technical college;

【通讯作者】 张存莉;

【机构】 西北农林科技大学延安职业技术学院陕西五丁生物科技有限公司

【摘要】 以荷叶方为原料,利用乳酸菌、酵母菌、醋酸菌发酵,制备荷叶方中药酵素,并应用胆酸盐结合试验研究其体外降血脂活性。结果显示,荷叶方经发酵后与甘氨胆酸钠的结合率为63.53%,与牛黄胆酸钠的结合率为63.51%,均高于发酵前的荷叶方及1 mg/mL考来烯胺,表明荷叶方中药酵素具有较好的体外降血脂活性并优于荷叶方中药浓缩液。

【Abstract】 Take lotus leaf square as raw material, Using lactic acid bacteria and yeast and acetobacter fermentation, Preparation of lotus leaf prescription Chinese medicine enzyme, The antihyperlipidemic activity was studied by cholate binding test in vitro.result display :After fermentation, the binding rate of lotus leaf formula with sodium glycocholate was 63.53%, The binding rate with sodium bezoar cholate was 63.51%, all of them were higher than those of Lotus leaf prescription and 1 mg/mL choleenamine before fermentation, which indicated that the traditional Chinese medicine enzyme of Lotus leaf prescription had better activity of lowering blood lipid in vitro and was better than that of concentrated Chinese medicine of He Ye Fang.

  • 【文献出处】 生物化工 ,Biological Chemical Engineering , 编辑部邮箱 ,2021年04期
  • 【分类号】R285
  • 【被引频次】3
  • 【下载频次】642
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