【摘要】 目的分析冠状动脉粥样硬化性心脏病(冠心病)患者行经皮冠脉介入治疗(PCI)成功开通冠状动脉慢性完全闭塞(CTO)是否能改善心绞痛症状,提高生活质量。方法连续纳入2016年1月至2018年1月于河南科技大学第一附属医院心内科行冠状动脉(冠脉)造影证实单支CTO病变且接受PCI的冠心病患者132例为研究对象,根据CTO病变是否开通,将其分CTO开通组(n=70)和CTO未开通组(n=62)。收集患者临床资料,随访前通过西雅图心绞痛量表(SAQ)完成心绞痛相关评分(主要评估患者生活质量、心绞痛症状),随访时间1年,随访后再次完善心绞痛相关评分;同时,记录患者主要不良心脑血管事件(MACCE)发生情况。结果通过对1年的随访,发现两组在总MACCE事件、心绞痛评分(躯体活动受限、心绞痛稳定状态、心绞痛发作频率、治疗满意)方面差异具有统计学意义(P<0.05),而在心绞痛评分量(疾病认知)方面,差异无明显统计学意义(P>0.05)。结论 CTO开通后能够有效改善冠心病患者心绞痛症状,提高生活质量,降低MACCE事件的发生率。更多还原

【Abstract】 Objective To analyze whether coronary artery chronic total occlusion(CTO) successfully opened by percutaneous coronary intervention in patients with coronary heart disease can improve angina symptoms and improve the quality of life of patients. Method A total of 132 consecutive patients with coronary artery disease confirmed by coronary angiography and treated with PCI in the Department of Cardiology, the First Affiliated Hospital of Henan University of science and technology from January 2016 to January 2018 were enrolled and divided into CTO open group(n=70) and CTO not opened group(n=62) according to whether the CTO lesion was opened or not.The basic clinical data of the patients were collected, and angina related scores(primary assessment of patients’ quality of life, angina symptoms) were completed by Seattle Angina scale(SAQ) before follow-up at 1 year, and the angina related scores were refined again after follow-up. Meanwhile, the occurrence of major adverse cardio cerebrovascular events(MACCE) was recorded. Results After one-year follow-up, the comparison between CTO-enabled group and CTO-disabled group showed that there were significant differences in total MACCE events, angina score(limited physical activity, stable angina, angina frequency and satisfactory treatment)(P<0.05), but there was no significant difference in angina score(disease cognition). Conclusion CTO can improve angina symptoms and quality of life in patients with coronary heart disease, and reduce the incidence of MACCE events.更多还原