【摘要】 目的探讨晚期食管癌患者实施多西紫杉醇+顺铂治疗的临床效果。方法选择河南科技大学第一附属医院2019年1月至2020年12月就诊的晚期食管癌患者80例,以随机数字表法分为对照组(常规治疗)和观察组(多西紫杉醇+顺铂治疗)各40例,对比两组疗效。结果观察组总有效率97.50%,对照组为80.00%,差异有统计学意义(P<0.05);观察组生存时间及肿瘤进展时间相较对照组为长,而生存质量评分(QOL)则高于对照组,差异有统计学意义(P<0.05)。结论将多西紫杉醇+顺铂治疗方案用于晚期食管癌患者,可优化临床疗效、延长生存时间、延缓肿瘤进展时间,同时可提高其生存质量,具积极推广价值。更多还原

【Abstract】 Objective To investigate the clinical effect of docetaxel plus cisplatin in the treatment of patients with advanced esophageal cancer and its effect on improving the quality of life. Methods 80 patients with advanced esophageal cancer in the first affiliated hospital of Henan university of science and technology from January 2019 to December 2020 were selected. The control group(treated with conventional treatment) and the observation group(treated with docetaxel and cisplatin) were 40 cases in each group. The curative effects of the two groups were compared. Results the total effective rate of the observation group was 97.50%, and that of the control group was 80.00%, with significant difference(P<0.05); the survival time and tumor progression time of the observation group were longer than those of the control group, while the quality of life score(QOL) was higher than that of the control group, with significant difference(P<0.05).Conclusion docetaxel plus cisplatin in the treatment of patients with advanced esophageal cancer can optimize the clinical efficacy, prolong the survival time, delay the time of tumor progression, and enhance the quality of life, which has positive promotion value.更多还原