【摘要】 目的探讨术前放化疗联合术后呼吸训练治疗中晚期食管癌的临床安全性和有效性。方法选择2018年10月至2020年5月在我院接受治疗的中晚期食管癌患者86例,用随机数字法分为对照组和观察组各43例。对照组采用术前放化疗联合手术治疗,观察组在对照组治疗的基础上加用术后呼吸训练,比较两组患者的治疗效果和并发症情况。结果观察组患者的肿瘤标志物均低于对照组,差异有统计学意义(P<0.05);观察组患者的6 min步行距离和步行呼吸频率较对照组明显改善(P<0.05),胸腔积液/积气低于对照组(P<0.05)。结论在中晚期食管癌患者的治疗中,采用术前放化疗联合术后呼吸训练可改善呼吸功能,减少并发症,促进患者的术后恢复。更多还原

【Abstract】 Objective To explore the clinical safety and effectiveness of using preoperative radiotherapy and chemotherapy combined with postoperative breathing training to treat patients with advanced esophageal cancer. Methods 86 patients with advanced esophageal cancer in our hospital from October 2018 to May 2020 were selected and divided into control group and observation group, 43 patients in each, randomly. The control group was treated by preoperative radiotherapy and chemotherapy combined with surgery. The observation group combined with postoperative respiratory training on the basis of the treatment of the control group. The treatment effects and complications of the two groups were compared. Results The tumor markers in the observation group were lower than those in the control group(P < 0.05). The 6-minute walking distance and walking respiratory rate of the observation group were significantly improved compared with those of the control group(P < 0.05), and the incidence of complications was significantly lower than that of the control group(P < 0.05). Conclusion For patients with advanced esophageal cancer, the combination of preoperative radiotherapy and chemotherapy with postoperative breathing training can improve respiratory function, reduce complications, promote the postoperative recovery of patients.更多还原